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Merck
CN

C8321

Cibacron Blue 3GA Agarose

saline suspension, Fast flow

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About This Item

UNSPSC Code:
23151817
PubChem Substance ID:
24893051
MDL number:
MFCD00043102

Key Documents

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InChI

1S/C29H20ClN7O11S3.3Na/c30-27-35-28(33-13-4-3-5-15(10-13)49(40,41)42)37-29(36-27)34-18-9-8-14(11-20(18)50(43,44)45)32-19-12-21(51(46,47)48)24(31)23-22(19)25(38)16-6-1-2-7-17(16)26(23)39;;;/h1-12,32H,31H2,(H,40,41,42)(H,43,44,45)(H,46,47,48)(H2,33,34,35,36,37);;;/q;3*+1/p-3

SMILES string

[Na+].[Na+].[Na+].Nc1c(cc(Nc2ccc(Nc3nc(Cl)nc(Nc4cccc(c4)S([O-])(=O)=O)n3)c(c2)S([O-])(=O)=O)c5C(=O)c6ccccc6C(=O)c15)S([O-])(=O)=O

InChI key

VZPXDCIISFTYOM-UHFFFAOYSA-K

form

saline suspension

extent of labeling

≥6 μmol per mL

matrix

Fast flow highly cross-linked 6% agarose

matrix attachment

triazine coupling

capacity

≥15 mg/mL binding capacity (human serum albumin)

storage temp.

2-8°C

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Application

Cibacron Blue 3GA-agarose is an agarose conjugate in saline suspension used in affinity chromatography, protein chromatography and dye resins.

Physical form

Suspension in 0.5 M NaCl containing 0.02% thimerosal

Disclaimer

For U.S. Customers: Contains mercury; Do not place in trash - dispose according to local, state, or federal laws.

Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
SLBD9750V
SLBD9750
080M5153
040M5154
090M5160

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Richa Gupta et al.
Molecular biology reports, 39(5), 5607-5614 (2011-12-23)
MspNI and MspNII, isoschizomers of prototype Type II restriction endonucleases AvaII and BstYI, were extracted from an extreme thermophile bacterium belonging to the genus Meiothermus, isolated from the hot sulphur springs in north Himalayan region of India where temperature and
María del Pilar Ferraris et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 879(26), 2741-2745 (2011-08-30)
The objective of this study was the development of affinity adsorbent particles with the appropriate characteristics to be applied in protein purification using the affinity ultrafiltration method. To prepare affinity macroligands Cibacron Blue 3GA, as a ligand molecule, was immobilized
Takashi Miura et al.
Free radical biology & medicine, 51(11), 2082-2089 (2011-10-04)
1,2-Naphthoquinone (1,2-NQ) is electrophilic, and forms covalent bonds with protein thiols, but its two-electron reduction product 1,2-dihydroxynaphthalene (1,2-NQH(2)) is not, so enzymes catalyzing the reduction with reduced pyridine nucleotides as cofactors could protect cells from electrophile-based chemical insults. To assess
Younis Baqi et al.
Journal of medicinal chemistry, 53(5), 2076-2086 (2010-02-12)
ecto-5'-Nucleotidase (eN, CD73) plays a major role in controlling extracellular adenosine levels. eN inhibitors have potential as novel drugs, for example, for the treatment of cancer. In the present study, we synthesized and investigated a series of 55 anthraquinone derivatives
Christa E Müller et al.
Bioorganic & medicinal chemistry letters, 16(23), 5943-5947 (2006-09-26)
Polyoxotungstates were identified as potent inhibitors of NTPDases1, 2, and 3. The most potent compound was K(6)H(2)[TiW(11)CoO(40)], exhibiting K(i) values of 0.140 microM (NTPDase1), 0.910 microM (NTPDase2), and 0.563 microM (NTPDase3). One of the compounds, (NH(4))(18)[NaSb(9)W(21)O(86)], was selective for NTPDases2
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