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C8321

Cibacron Blue 3GA Agarose

Name: Cibacron Blue 3GA Agarose
Brand: SIGMA

saline suspension, Fast flow

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About This Item

UNSPSC Code:

23151817

PubChem Substance ID:

24893051

MDL number:

MFCD00043102

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form

saline suspension

extent of labeling

≥6 μmol per mL

matrix

Fast flow highly cross-linked 6% agarose

matrix attachment

triazine coupling

capacity

≥15 mg/mL binding capacity (human serum albumin)

storage temp.

2-8°C

SMILES string

[Na+].[Na+].[Na+].Nc1c(cc(Nc2ccc(Nc3nc(Cl)nc(Nc4cccc(c4)S([O-])(=O)=O)n3)c(c2)S([O-])(=O)=O)c5C(=O)c6ccccc6C(=O)c15)S([O-])(=O)=O

InChI

1S/C29H20ClN7O11S3.3Na/c30-27-35-28(33-13-4-3-5-15(10-13)49(40,41)42)37-29(36-27)34-18-9-8-14(11-20(18)50(43,44)45)32-19-12-21(51(46,47)48)24(31)23-22(19)25(38)16-6-1-2-7-17(16)26(23)39;;;/h1-12,32H,31H2,(H,40,41,42)(H,43,44,45)(H,46,47,48)(H2,33,34,35,36,37);;;/q;3*+1/p-3

InChI key

VZPXDCIISFTYOM-UHFFFAOYSA-K

Application

Cibacron Blue 3GA-agarose is an agarose conjugate in saline suspension used in affinity chromatography, protein chromatography and dye resins.

Physical form

Suspension in 0.5 M NaCl containing 0.02% thimerosal

Disclaimer

For U.S. Customers: Contains mercury; Do not place in trash - dispose according to local, state, or federal laws.

Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Characterization of MspNI (G/GWCC) and MspNII (R/GATCY), novel thermostable Type II restriction endonucleases from Meiothermus sp., isoschizomers of AvaII and BstYI.

Richa Gupta et al.

Molecular biology reports, 39(5), 5607-5614 (2011-12-23)

MspNI and MspNII, isoschizomers of prototype Type II restriction endonucleases AvaII and BstYI, were extracted from an extreme thermophile bacterium belonging to the genus Meiothermus, isolated from the hot sulphur springs in north Himalayan region of India where temperature and

Glyceraldehyde-3-phosphate dehydrogenase as a quinone reductase in the suppression of 1,2-naphthoquinone protein adduct formation.

Takashi Miura et al.

Free radical biology & medicine, 51(11), 2082-2089 (2011-10-04)

1,2-Naphthoquinone (1,2-NQ) is electrophilic, and forms covalent bonds with protein thiols, but its two-electron reduction product 1,2-dihydroxynaphthalene (1,2-NQH(2)) is not, so enzymes catalyzing the reduction with reduced pyridine nucleotides as cofactors could protect cells from electrophile-based chemical insults. To assess

Affinity adsorption of lysozyme on a macroligand prepared with Cibacron Blue 3GA attached to yeast cells.

María del Pilar Ferraris et al.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 879(26), 2741-2745 (2011-08-30)

The objective of this study was the development of affinity adsorbent particles with the appropriate characteristics to be applied in protein purification using the affinity ultrafiltration method. To prepare affinity macroligands Cibacron Blue 3GA, as a ligand molecule, was immobilized

Selective nucleoside triphosphate diphosphohydrolase-2 (NTPDase2) inhibitors: nucleotide mimetics derived from uridine-5'-carboxamide.

Andreas Brunschweiger et al.

Journal of medicinal chemistry, 51(15), 4518-4528 (2008-07-18)

Ecto-nucleoside triphosphate diphosphohydrolases (E-NTPDases, subtypes 1, 2, 3, 8 of NTPDases) dephosphorylate nucleoside tri- and diphosphates to the corresponding di- and monophosphates. In the present study we synthesized adenine and uracil nucleotide mimetics, in which the phosphate residues were replaced

Combinatorial synthesis of anilinoanthraquinone derivatives and evaluation as non-nucleotide-derived P2Y2 receptor antagonists.

Stefanie Weyler et al.

Bioorganic & medicinal chemistry letters, 18(1), 223-227 (2007-11-17)

A library of anilinoanthraquinone derivatives was synthesized by parallel Ullmann coupling reaction of bromaminic acid with aniline derivatives in solution using a compact parallel synthesizer. The products were purified by HPLC and evaluated as antagonists at mouse and human P2Y2

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