Anti-CX3CR-1, N-Terminal antibody produced in rabbit

CX3CR1 is a fractalkaine receptor that regulates chemotaxis and adhesion in white blood cells . Impairment of CX3CR1 function has been associated with defects in hippocampal cognition and neuronal plasticity . Cells expressing CX3CR1 receptors inhibit T-cell proliferation and subsequently prevent intestinal inflammation . Anti-CX3CR-1, N-Terminal antibody is specific for CX3CR1 by immunoblotting using human spleen tissue lysate. The antibody also reacts with mouse and rat CX3CR1.

synthetic peptide corresponding to the N-terminal and amino acids 2-21 of human CX3CR1 (V28, CMKBRL1). This sequence differs from mouse and rat by four amino acids.

Anti-CX3CR-1, N-Terminal antibody is suitable for use in immunoblot (approx. 50kDa), western blot (0.5-1 μg/ml) using human spleen lysate) and immunohistochemistry (~2 μg/mL using human heart tissue).

Solution in 0.01 M phosphate buffered saline containing 0.02% sodium azide.

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