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Merck
CN

C8917

Sigma-Aldrich

Cystatin from chicken egg white

lyophilized powder

Synonym(s):

Cysteine protease inhibitor

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About This Item

CAS Number:
81989-95-9
MDL number:
MFCD00130887
UNSPSC Code:
12352202
NACRES:
NA.77

Key Documents

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form

lyophilized powder

potency

≥40 BAEE units per mg protein 50% inhibition of papain (pH 6.8 at 40 °C)

mol wt

13 kDa

solubility

water: 1.0-1.1 mg/mL, clear to slightly hazy, colorless

storage temp.

2-8°C

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Application

Cysteine proteases inhibitor, including dipeptidyl peptidase III. Effective concentration equimolar with protease.
Inhibitor of cysteine proteases, including papain and dipeptidyl peptidase III. Effective concentration equimolar with protease. A docking model has been proposed for the mechanism of inhibition of papain.

Packaging

Package size based on protein content.

Disclaimer

Unstable to freezing unless in the presence of 20% glycerol or buffered to pH 7.5.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

常规特殊物品
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Certificates of Analysis (COA)

Lot/Batch Number
11170414
113M4079V
067M4184V
126M4103V
014M4003V

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Hana Dvořáková et al.
Frontiers in cellular and infection microbiology, 10, 66-66 (2020-03-17)
Schistosomula (the post-infective stages) of the neurotropic schistosome Trichobilharzia regenti possess multiple isoforms of cathepsin B1 peptidase (TrCB1.1-TrCB1.6) with involvement in nutrient digestion. The comparison of substrate preferences of TrCB1.1 and TrCB1.4 showed that TrCB1.4 had a very narrow substrate
Yong Ku Cho et al.
Journal of immunological methods, 341(1-2), 117-126 (2008-12-02)
Yeast antibody display has found a wide variety of applications including antibody affinity maturation, epitope mapping, and library screening. Here we report a yeast display immunoprecipitation (YDIP) technique that employs yeast cells displaying single-chain antibody fragments (scFv) on their surface

Articles

Papain, Cysteine Protease, Properties & Products

Uncover properties and applications of the cysteine protease papain and find inhibitors, substrates, and other papain products.

半胱氨酸蛋白酶——木瓜蛋白酶的特性和产品

木瓜蛋白酶是肽酶C1家族的一种半胱氨酸蛋白酶。它由单一多肽链组成，含有三个二硫键和一个酶活性所必需的巯基。

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