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Merck
CN

C9464

Cholesterol Esterase from porcine pancreas

lyophilized powder, ≥15,000 units/g protein

Synonym(s):

Cholesterol Esterase from hog pancreas, Sterol-ester acylhydrolase

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About This Item

CAS Number:
UNSPSC Code:
12352204
EC Number:
232-808-6
MDL number:
EC Number:
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form

lyophilized powder

specific activity

≥15,000 units/g protein

mol wt

dimer 167 kDa

composition

Protein, ~70%

storage temp.

−20°C

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Analysis Note

Protein determined by biuret.

Other Notes

Contains potassium phosphate buffer salts and stabilizer.
One unit will hydrolyze 1.0 μmole of cholesteryl oleate to cholesterol and oleic acid per min at pH 7.0 at 37 °C in the presence of taurocholate.

pictograms

Health hazard

signalword

Danger

hcodes

Hazard Classifications

Resp. Sens. 1

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Yong-lan Huang et al.
Zhonghua er ke za zhi = Chinese journal of pediatrics, 50(8), 601-605 (2012-11-20)
To explore the clinical characteristics of Wolman disease and diagnostic methods using enzymatic and molecular analysis. Lysosomal acid lipase activity was measured using 4-methylumbelliferyl oleate in the leukocytes of an infant suspected of Wolman disease and LIPA gene mutational analysis
Myung Hee Moon et al.
Experimental & molecular medicine, 44(10), 603-614 (2012-08-04)
Higher levels of body fat are associated with an increased risk for development numerous adverse health conditions. FTY720 is an immune modulator and a synthetic analogue of sphingosine 1-phosphate (S1P), activated S1P receptors and is effective in experimental models of
Joanna Karbowska et al.
Steroids, 77(13), 1359-1365 (2012-09-07)
Dehydroepiandrosterone (DHEA) reduces body fat in rodents and humans, and increases glycerol release from isolated rat epididymal adipocytes and human visceral adipose tissue explants. It suggests that DHEA stimulates triglyceride hydrolysis in adipose tissue; however, the mechanisms underlying this action
Maria J Pereira et al.
Molecular and cellular endocrinology, 365(2), 260-269 (2012-11-20)
Cyclosporin A (CsA), tacrolimus and rapamycin are immunosuppressive agents (IAs) associated with insulin resistance and dyslipidemia, although their molecular effects on lipid metabolism in adipose tissue are unknown. We explored IAs effects on lipolysis, lipid storage and expression of genes
Nitika A Gupta et al.
The American journal of pathology, 181(5), 1693-1701 (2012-09-11)
Nonalcoholic fatty liver disease is an increasingly prevalent spectrum of conditions characterized by excess fat deposition within hepatocytes. Affected hepatocytes are known to be highly susceptible to ischemic insults, responding to injury with increased cell death, and commensurate liver dysfunction.

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