Skip to Content
Merck
CN

C9635

DL-p-Chloroamphetamine hydrochloride

≥94% (HPLC)

Synonym(s):

4-Chloro-α-methylphenethylamine hydrochloride, PCA

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Linear Formula:
ClC6H4CH2CH(CH3)NH2·HCl
CAS Number:
3706-38-5
Molecular Weight:
206.11
NACRES:
NA.77
PubChem Substance ID:
24893180
UNSPSC Code:
12352103
MDL number:
MFCD00013014
Assay:
≥94% (HPLC)
Form:
powder

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

InChI

1S/C9H12ClN.ClH/c1-7(11)6-8-2-4-9(10)5-3-8;/h2-5,7H,6,11H2,1H3;1H

SMILES string

Cl.CC(N)Cc1ccc(Cl)cc1

InChI key

DZAANUYJOGCNLL-UHFFFAOYSA-N

assay

≥94% (HPLC)

form

powder

drug control

Home Office Schedule 1; regulated under CDSA - not available from Sigma-Aldrich Canada

color

white to off-white

mp

168-170 °C (lit.)

solubility

DMSO: >20 mg/mL, H2O: >20 mg/mL

storage temp.

−20°C

Looking for similar products? Visit Product Comparison Guide

Biochem/physiol Actions

Neurotoxic on prolonged administration or at high dosage; substrate for the serotonin transporter that releases serotonin from axon terminals by a nonexocytotic mechanism and blocks the reuptake of serotonin; inhibits tryptophan hydroxylase.

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Repr. 2 - STOT RE 2 - STOT SE 3

target_organs

Brain, Central nervous system

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Regulatory Information

新产品
This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
0000072751
0000049084
0000069802
0000021341
0000004077

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Takumi Oti et al.
International journal of molecular sciences, 22(19) (2021-10-14)
Male sexual function in mammals is controlled by the brain neural circuits and the spinal cord centers located in the lamina X of the lumbar spinal cord (L3-L4). Recently, we reported that hypothalamic oxytocin neurons project to the lumbar spinal
P Scholze et al.
The Journal of pharmacology and experimental therapeutics, 293(3), 870-878 (2000-06-28)
HEK 293 cells stably expressing the human serotonin transporter (hSERT) were grown on coverslips, preincubated with [(3)H]5-hydroxytryptamine (5-HT), and superfused. Substrates of the hSERT [e.g., p-chloroamphetamine (PCA)], increased the basal efflux of [(3)H]5-HT in a concentration-dependent manner. 5-HT reuptake blockers
H Harrington Cleveland et al.
Development and psychopathology, 27(1), 51-67 (2015-02-03)
Data drawn from the in-home subsample of the PROSPER intervention dissemination trial were used to investigate the moderation of intervention effects on underage alcohol use by maternal involvement and candidate genes. The primary gene examined was dopamine receptor D4 (DRD4).
Revel S M Drummond et al.
Plant physiology, 168(2), 735-751 (2015-04-26)
Plants alter their development in response to changes in their environment. This responsiveness has proven to be a successful evolutionary trait. Here, we tested the hypothesis that two key environmental factors, light and nutrition, are integrated within the axillary bud
Joke Baute et al.
Genome biology, 16, 168-168 (2015-09-12)
To sustain the global requirements for food and renewable resources, unraveling the molecular networks underlying plant growth is becoming pivotal. Although several approaches to identify genes and networks involved in final organ size have been proven successful, our understanding remains
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service