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Merck
CN

D0163

Dequalinium acetate

~90%

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About This Item

Empirical Formula (Hill Notation):
C30H40N4 · C4H6O4
CAS Number:
Molecular Weight:
574.75
UNSPSC Code:
12352200
EC Number:
223-712-5
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InChI key

IWYNVAJACBPVLT-UHFFFAOYSA-N

InChI

1S/C30H38N4.2C2H4O2/c1-23-21-27(31)25-15-9-11-17-29(25)33(23)19-13-7-5-3-4-6-8-14-20-34-24(2)22-28(32)26-16-10-12-18-30(26)34;2*1-2(3)4/h9-12,15-18,21-22,31-32H,3-8,13-14,19-20H2,1-2H3;2*1H3,(H,3,4)

assay

~90%

Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Diana Lyrawati et al.
Pharmaceutical research, 28(11), 2848-2862 (2011-08-13)
We describe a novel strategy for expression of GFP in mammalian mitochondria. The key components of the strategy were an artificially created mitochondrial genome pmtGFP and a DQAsome transfection system. Using immunofluorescence and a combination of immunohistochemical and molecular based
Lucia Pajuelo et al.
Investigational new drugs, 29(6), 1156-1163 (2010-06-05)
B-cell chronic lymphocytic leukemia (B-CLL) is an abnormal neoplasic proliferation of B cells, which accumulate mainly in the bone marrow and blood preventing both B cells development in the lymph nodes and the ability to fight against infection. The antitumor
Ernst Rainer Weissenbacher et al.
Gynecologic and obstetric investigation, 73(1), 8-15 (2011-12-30)
To investigate if vaginal application of dequalinium chloride (DQC, Fluomizin®) is as effective as vaginal clindamycin (CLM) in the treatment of bacterial vaginosis (BV). This was a multinational, multicenter, single-blind, randomized trial in 15 centers, including 321 women. They were
Kristen M Smith et al.
EMBO molecular medicine, 2(9), 371-384 (2010-08-20)
Neuroblastoma (NB) is the most deadly extra-cranial solid tumour in children necessitating an urgent need for effective and less toxic treatments. One reason for the lack of efficacious treatments may be the inability of existing drugs to target the tumour-initiating
Mar Orzáez et al.
Apoptosis : an international journal on programmed cell death, 16(5), 460-467 (2011-02-23)
Inhibitor of apoptosis proteins (IAPs) regulate the activity of caspases in apoptosis. The human X chromosome-encoded IAP (XIAP) is one of the more potent members of the IAP family and it has been described as a central regulator of apoptosis.

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