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Merck
CN

D017

Sigma-Aldrich

m-Tyramine hydrochloride

solid, ≥98% (HPLC)

Synonym(s):

3-Hydroxyphenethylamine hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C8H11NO · HCl
CAS Number:
3458-98-8
Molecular Weight:
173.64
EC Number:
222-396-6
MDL number:
MFCD00040591
UNSPSC Code:
12352200
PubChem Substance ID:
24893216

Key Documents

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Assay

≥98% (HPLC)

form

solid

storage condition

protect from light

color

off-white to tan

solubility

H2O: ≥10 mg/mL

SMILES string

Cl[H].NCCc1cccc(O)c1

InChI

1S/C8H11NO.ClH/c9-5-4-7-2-1-3-8(10)6-7;/h1-3,6,10H,4-5,9H2;1H

InChI key

GTIWCKXKQGMMQZ-UHFFFAOYSA-N

Biochem/physiol Actions

Dopamine receptor agonist; biological precursor to dopamine.

Disclaimer

Photosensitive

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Precautionary Statements

P261 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
116K4604
063K4620

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P H Yu et al.
Journal of neurochemistry, 45(3), 836-843 (1985-09-01)
An arylamine sulfotransferase (PST-M) from human brain cortex that is involved in the formation of O-sulfate esters of monoamines has been purified 272-fold by ammonium sulfate fractionation, gel filtration, DEAE-cellulose ion-exchange chromatography, chromatofocussing, and hydroxyapatite chromatography. A molecular weight of
S C Yeung et al.
General pharmacology, 16(5), 517-519 (1985-01-01)
The concentration of homovanillic acid and p-tyramine in the female corpus striatum were increased after ovariectomy. The increases were reversed by chronic administration of estradiol benzoate and potentiated by progesterone. It is proposed that these changes are the consequence of
P S McQuade et al.
European journal of pharmacology, 83(3-4), 277-282 (1982-09-24)
The concentrations of p-tyramine (p-TA), m-tyramine (m-TA), dopamine (DA) and their principal metabolites, p-hydroxyphenylacetic acid (p-HPAA), m-hydroxyphenylacetic acid (m-HPAA) and homovanillic acid (HVA) were determined in the corpus striatum of Swiss mice at various times after the subcutaneous administration of
D L Murphy et al.
Journal of neural transmission. Supplementum, 52, 39-48 (1998-06-13)
Marked, dose-dependent elevations in the urinary excretion of phenylethylamine, para-tyramine, and meta-tyramine were observed in depressed patients treated for three or more weeks with 10, 30, or 60 mg/day of the partially-selective inhibitor of MAO-B, selegiline (l-deprenyl). In comparative studies
P L Walker et al.
Annals of clinical biochemistry, 25 ( Pt 3), 304-309 (1988-05-01)
A simple, reliable method for the analysis of urinary meta- and para-tyramine has been developed. Sample purification was achieved by a weak anion-exchange column, followed by extraction into ethyl acetate at pH 10.2. The heptafluorobutyryl derivative was measured by packed
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