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Merck
CN

D017

m-Tyramine hydrochloride

solid, ≥98% (HPLC)

Synonym(s):

3-Hydroxyphenethylamine hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C8H11NO · HCl
CAS Number:
Molecular Weight:
173.64
UNSPSC Code:
12352200
PubChem Substance ID:
EC Number:
222-396-6
MDL number:
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InChI key

GTIWCKXKQGMMQZ-UHFFFAOYSA-N

InChI

1S/C8H11NO.ClH/c9-5-4-7-2-1-3-8(10)6-7;/h1-3,6,10H,4-5,9H2;1H

SMILES string

Cl[H].NCCc1cccc(O)c1

assay

≥98% (HPLC)

form

solid

storage condition

protect from light

color

off-white to tan

solubility

H2O: ≥10 mg/mL

Biochem/physiol Actions

Dopamine receptor agonist; biological precursor to dopamine.

Disclaimer

Photosensitive

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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D A Durden et al.
Neurochemical research, 18(9), 995-1002 (1993-09-01)
Using a new ultrasensitive method the trace biogenic amines, phenylethylamine, meta-tyramine and para-tyramine have been quantitated in brain regions obtained from a single rat. Phenylethylamine concentrations in ng/g wet tissue (mean +/- std. error) were as follows: caudate 2.71 +/-
P L Walker et al.
Annals of clinical biochemistry, 25 ( Pt 3), 304-309 (1988-05-01)
A simple, reliable method for the analysis of urinary meta- and para-tyramine has been developed. Sample purification was achieved by a weak anion-exchange column, followed by extraction into ethyl acetate at pH 10.2. The heptafluorobutyryl derivative was measured by packed
S C Yeung et al.
General pharmacology, 16(5), 517-519 (1985-01-01)
The concentration of homovanillic acid and p-tyramine in the female corpus striatum were increased after ovariectomy. The increases were reversed by chronic administration of estradiol benzoate and potentiated by progesterone. It is proposed that these changes are the consequence of
H Wayment et al.
Journal of neurochemistry, 70(5), 1941-1949 (1998-05-08)
Experiments were conducted to determine how (-)-cocaine and S(+)-amphetamine binding sites relate to each other and to the catechol substrate site on the striatal dopamine transporter (sDAT). In controls, m-tyramine and S(+)-amphetamine caused release of dopamine from intracellular stores at
D L Murphy et al.
Journal of neural transmission. Supplementum, 52, 39-48 (1998-06-13)
Marked, dose-dependent elevations in the urinary excretion of phenylethylamine, para-tyramine, and meta-tyramine were observed in depressed patients treated for three or more weeks with 10, 30, or 60 mg/day of the partially-selective inhibitor of MAO-B, selegiline (l-deprenyl). In comparative studies

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