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Merck
CN

D0286

13,14-Dihydro-15-ketoprostaglandin E2 solution

~90%

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About This Item

Empirical Formula (Hill Notation):
C20H32O5
CAS Number:
Molecular Weight:
352.47
UNSPSC Code:
12352115
PubChem Substance ID:
MDL number:
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InChI

1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,16-17,19,23H,2-3,5-6,8-14H2,1H3,(H,24,25)/b7-4-/t16-,17-,19-/m1/s1

SMILES string

CCCCCC(=O)CC[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O

InChI key

CUJMXIQZWPZMNQ-XYYGWQPLSA-N

assay

~90%

form

solution

shipped in

dry ice

storage temp.

−20°C

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Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

3 - Flammable liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Regulatory Information

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[Double-blind study of the effect of various intra-arterial/intravenous prostaglandin E1 doses on hemodynamics and prostaglandin E1 metabolites].
G Rudofsky et al.
VASA. Supplementum, 33, 345-345 (1991-01-01)
W Heuwieser et al.
Prostaglandins, 45(1), 35-46 (1993-01-01)
A study was conducted to measure the blood plasma concentrations of prostaglandin F2 alpha (PGF2 alpha), 13,14-dihydro-15-keto-prostaglandin F2 alpha (PGFM), prostaglandin E2 (PGE2) and 13,14-dihydro-15-keto-prostaglandin E2 (PGEM) in the jugular vein, umbilical vein and artery and uterine vein of 18
L Cheng et al.
The Journal of clinical endocrinology and metabolism, 77(3), 873-877 (1993-09-01)
The widespread tissue distribution of prostaglandin dehydrogenase (PGDH), the main enzyme for the metabolism and deactivation of prostaglandin (PG), suggests that local effective levels of PG are controlled by catabolism. Previous reports have suggested that after the administration of mifepristone
S Sakuma et al.
Prostaglandins, leukotrienes, and essential fatty acids, 51(6), 425-430 (1994-12-01)
The effect of 13-hydroperoxyoctadecadienoic acid (13-HPODE), a hydroperoxy adduct of linoleic acid (LA), on the activities of prostaglandin (PG) synthesizing and catabolizing enzymes in rabbit gastric antral mucosa was examined. 13-HPODE had no effect on the synthesis of PGE2, PGF2
F J Lüke et al.
Journal of immunological methods, 148(1-2), 217-223 (1992-04-08)
We describe a time-resolved fluoroimmunoassay method for the determination of 13,14-dihydro-15-ketoprostaglandin E2 (PGEM) and 13,14-dihydro-15-ketoprostaglandin F2 alpha (PGFM) in femtomolar ranges. Polyclonal antibodies were raised in rabbits and the antigen was labelled with europium by the avidin-biotin technique. A second

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