D1286
Monoclonal Anti-Desmosomal Protein antibody produced in mouse
clone ZK-31, ascites fluid
Sign Into View Organizational & Contract Pricing
Select a Size
About This Item
MDL number:
UNSPSC Code:
12352203
biological source
mouse
conjugate
unconjugated
antibody form
ascites fluid
clone
ZK-31, monoclonal
contains
15 mM sodium azide
species reactivity
human, animal
technique(s)
indirect immunofluorescence: 1:400 using frozen sections of human tissue.
microarray: suitable
isotype
IgG1
shipped in
dry ice
storage temp.
−20°C
Gene Information
human ... DSC1(1823), DSC2(1824), DSC3(1825), DSG1(1828)
Immunogen
human epidermal keratins
Biochem/physiol Actions
The antibody localizes an epitope on desmosomes, but does not show reaction with hemidesmosomes. The product may be used for immunoperoxidase and immunofluorescent staining of frozen sections of human and animal tissues or densely grown monolayers of human and animal cells.
Regulatory Information
新产品
This item has
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
J L R Williams et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 295(4), R1204-R1213 (2008-08-16)
Maintaining placental syncytiotrophoblast, a specialized multinucleated transport epithelium, is essential for normal human pregnancy. Syncytiotrophoblast continuously renews through differentiation and fusion of cytotrophoblast cells, under paracrine control by syncytiotrophoblast production of human chorionic gonadotropin (hCG). We hypothesized that K(+) channels
A B Lang et al.
Experimental cell biology, 54(2), 61-72 (1986-01-01)
Immunohistological analysis of human tissue using monoclonal antibodies against cytokeratins, which are confined to cells of epithelial origin, is a valuable technique. Using human epidermal keratins as antigen, we prepared monoclonal antibodies against cytokeratins (ZK1, ZK7, ZK61 and ZK99) and
Gavin P Collett et al.
PloS one, 5(5), e10529-e10529 (2010-05-14)
Fusion of placental villous cytotrophoblasts with the overlying syncytiotrophoblast is essential for the maintenance of successful pregnancy, and disturbances in this process have been implicated in pathological conditions such as pre-eclampsia and intra-uterine growth retardation. Caveolin-1 has been shown to
Gavin P Collett et al.
PloS one, 7(1), e30453-e30453 (2012-01-25)
Fusion of placental villous cytotrophoblasts with the overlying syncytiotrophoblast is essential for the maintenance of successful pregnancy, and disturbances in this process have been implicated in pathological conditions such as pre-eclampsia and intra-uterine growth retardation. In this study we examined
Pascale Gerbaud et al.
Endocrinology, 152(12), 5017-5028 (2011-09-29)
Placental development is markedly abnormal in trisomy 21 (T21) pregnancies. We hypothesized that abnormal paracrine cross talk between the fetal mesenchymal core and the trophoblast might be involved in the defect of syncytiotrophoblast formation and function. In a large series
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service