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D1414

Droperidol

Name: Droperidol
Brand: SIGMA

dopamine subtype 2 receptor antagonist, powder

Synonym(s):

1-[1-[3-(p-Fluorobenzoyl)propyl]-1,2,3,6-tetrahydro-4-pyridyl]-2-benzimidazolinone

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About This Item

Empirical Formula (Hill Notation):

C₂₂H₂₂FN₃O₂

CAS Number:

548-73-2

Molecular Weight:

379.43

NACRES:

NA.77

PubChem Substance ID:

24278357

UNSPSC Code:

41116107

EC Number:

208-957-8

MDL number:

MFCD00083290

Form:

powder

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Properties

Product Name

Droperidol,

form

powder

Quality Segment

200

originator

Johnson & Johnson

storage temp.

2-8°C

SMILES string

Fc1ccc(cc1)C(=O)CCCN2CCC(=CC2)N3C(=O)Nc4ccccc34

InChI

1S/C22H22FN3O2/c23-17-9-7-16(8-10-17)21(27)6-3-13-25-14-11-18(12-15-25)26-20-5-2-1-4-19(20)24-22(26)28/h1-2,4-5,7-11H,3,6,12-15H2,(H,24,28)

InChI key

RMEDXOLNCUSCGS-UHFFFAOYSA-N

Gene Information

human ... DRD1(1812), DRD2(1813), DRD3(1814), DRD4(1815), HTR2A(3356), KCNH1(3756), KCNH2(3757)

Description

Biochem/physiol Actions

Droperidol is a potent antagonist of dopamine subtype 2 receptor. It is an antipsychotic, which is used to treat acute behavioral anomalies. It helps to manage postoperative nausea and vomiting.

D₁, D₂ dopamine receptor antagonist; butyrophenone antipsychotic and anti-emetic.

Features and Benefits

This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

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pictograms

GHS07

signalword

Warning

hcodes

H302

pcodes

P301 + P312 + P330

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c