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Merck
CN

D157406

2-Dimethylaminoethanol

Synonym(s):

N,N-Dimethyl-2-hydroxyethylamine, N,N-Dimethylethanolamine, Jeffcat DMEA

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About This Item

Linear Formula:
(CH3)2NCH2CH2OH
CAS Number:
108-01-0
Molecular Weight:
89.14
EC Number:
203-542-8
UNSPSC Code:
12352100
PubChem Substance ID:
329798704
Beilstein/REAXYS Number:
1209235
MDL number:
MFCD00002846

Key Documents

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InChI key

UEEJHVSXFDXPFK-UHFFFAOYSA-N

InChI

1S/C4H11NO/c1-5(2)3-4-6/h6H,3-4H2,1-2H3

SMILES string

CN(C)CCO

vapor pressure

100 mmHg ( 55 °C), 6.12 mmHg ( 20 °C)

refractive index

n20/D 1.4294 (lit.)

bp

134-136 °C (lit.)

mp

−70 °C (lit.)

density

0.886 g/mL at 20 °C (lit.)

Quality Level

100

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signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1B - STOT SE 3

target_organs

Respiratory system

Storage Class

3 - Flammable liquids

wgk

WGK 1

flash_point_f

104.0 °F - Seta closed cup

flash_point_c

40 °C - Seta closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

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Tadashi Tatsumi et al.
Bioorganic & medicinal chemistry, 18(7), 2720-2727 (2010-03-17)
Effects of retro-inverso (RI) modifications of HTLV-1 protease inhibitors containing a hydroxyethylamine isoster backbone were clarified. Construction of the isoster backbone was achieved by a stereoselective aldol reaction. Four diastereomers with different configurations at the isoster hydroxyl site and the
Olivier Blin et al.
Psychopharmacology, 207(2), 201-212 (2009-09-17)
Dimethylaminoethanol pyroglutamate (DMAE p-Glu) is a compound resulting from the reaction between dimethylaminoethanol (an indirect precursor of acetylcholine) and pyroglutamic acid (a cyclic derivative of glutamic acid having procholinergic properties and promnesic effects in both animals and man). The present
B Sommerfeld
Phytomedicine : international journal of phytotherapy and phytopharmacology, 14(11), 711-715 (2007-10-10)
Tricutan is a combination product of herbal extracts traditionally used for treatment of skin conditions, together with dimethylaminoethanol. The effectiveness of Tricutan in improving skin firmness and elasticity in photoaged facial skin was examined in a randomised, placebo-controlled, double-blind, split-face
Dominique Slaets et al.
European journal of nuclear medicine and molecular imaging, 37(11), 2136-2145 (2010-06-18)
[(18)F]Fluoromethylcholine ([(18)F]FCho) is a radiotracer generally used for tumour visualization in patients. Due to high levels of dimethylaminoethanol (DMAE) remaining in [(18)F]FCho solutions synthesized by currently available methods, tumour visualization might be compromised. An improved purification method involving an optimized
K M Houston et al.
Parasitology, 135(Pt 1), 55-61 (2007-09-26)
Juvenile female Litomosoides sigmodontis secrete a protein (Juv-p120) highly modified with dimethylethanolamine (DMAE). In an attempt to establish the source of this decoration worms were pulsed with [3H]-choline and [3H]-ethanolamine and the radio-isotope labelled products analysed. Both isotope labels were
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