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Merck
CN

D4067

Delta Sleep Inducing Peptide

≥97% (HPLC)

Synonym(s):

DSIP, Emideltide, Sleep inducing peptide, Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu

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About This Item

Empirical Formula (Hill Notation):
C35H48N10O15
CAS Number:
62568-57-4
Molecular Weight:
848.81
UNSPSC Code:
12352200
MDL number:
MFCD00076883

Key Documents

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InChI key

ZRZROXNBKJAOKB-GFVHOAGBSA-N

InChI

1S/C35H48N10O15/c1-16(41-32(56)20(36)9-18-11-37-21-6-4-3-5-19(18)21)30(54)39-12-25(47)38-13-26(48)44-23(10-29(52)53)34(58)42-17(2)31(55)45-24(15-46)33(57)40-14-27(49)43-22(35(59)60)7-8-28(50)51/h3-6,11,16-17,20,22-24,37,46H,7-10,12-15,36H2,1-2H3,(H,38,47)(H,39,54)(H,40,57)(H,41,56)(H,42,58)(H,43,49)(H,44,48)(H,45,55)(H,50,51)(H,52,53)(H,59,60)/t16-,17-,20-,22-,23-,24-/m0/s1

SMILES string

C[C@H](NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(=O)NCC(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(O)=O

assay

≥97% (HPLC)

storage temp.

−20°C

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
044K49602
044K49601

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The delta-sleep inducing peptide (DSIP) increases duration of sleep in rats.
S Kafi et al.
Neuroscience letters, 13(2), 169-172 (1979-07-01)
The delta sleep inducing peptide (DSIP). Comparative properties of the original and synthetic nonapeptide.
M Monnier et al.
Experientia, 33(4), 548-552 (1977-04-15)
G A Schoenenberger et al.
Proceedings of the National Academy of Sciences of the United States of America, 74(3), 1282-1286 (1977-03-01)
A peptide that induces slow-wave (delta) and spindles electroencephalogram enhancement after intraventricular (brain) infusion has been isolated from rabbits and given the name delta-sleep-inducing peptide (DSIP). Amino acid seqeunce: Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu. This compound, five possible metabolic products (containing residues 1--8, 2--9

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