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D4072

Delta Sleep Inducing Peptide

Name: Delta Sleep Inducing Peptide
Brand: SIGMA

Synonym(s):

DSIP, Emideltide, Sleep inducing peptide, Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu

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About This Item

Empirical Formula (Hill Notation):

C₃₅H₄₈N₁₀O₁₅

CAS Number:

62568-57-4

Molecular Weight:

848.81

NACRES:

NA.32

PubChem Substance ID:

329798794

UNSPSC Code:

12352200

MDL number:

MFCD00076883

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form

powder

storage temp.

−20°C

SMILES string

C[C@H](NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(=O)NCC(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(O)=O

InChI

1S/C35H48N10O15/c1-16(41-32(56)20(36)9-18-11-37-21-6-4-3-5-19(18)21)30(54)39-12-25(47)38-13-26(48)44-23(10-29(52)53)34(58)42-17(2)31(55)45-24(15-46)33(57)40-14-27(49)43-22(35(59)60)7-8-28(50)51/h3-6,11,16-17,20,22-24,37,46H,7-10,12-15,36H2,1-2H3,(H,38,47)(H,39,54)(H,40,57)(H,41,56)(H,42,58)(H,43,49)(H,44,48)(H,45,55)(H,50,51)(H,52,53)(H,59,60)/t16-,17-,20-,22-,23-,24-/m0/s1

InChI key

ZRZROXNBKJAOKB-GFVHOAGBSA-N

General description

Delta sleep inducing peptide (DSIP) is a nonapeptide which was isolated from the rabbit brain. It is synthesized in the hypothalamus and is present in small amounts in the blood.

Biochem/physiol Actions

DSIP promotes sleep by targeting various areas of the brain. The peptide is easily absorbed from the gut and is not denatured by enzymes. It crosses the blood-brain barrier easily. DSIP influences the circadian rhythm in humans. Low concentrations of the peptide are observed in patients with schizophrenia and depression.

Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

涉药品监管产品

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Certificates of Analysis (COA)

Lot/Batch Number

SLBK6326

SLBK6162

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Delta sleep-inducing peptide

Pollard BJ and Pomfrett CJD

European Journal of Anaesthesiology, 18(7), 419-422 (2001)

Influence of the amino acid composition on the ionization efficiencies of small peptides.

Piia Liigand et al.

Journal of mass spectrometry : JMS, 54(6), 481-487 (2019-03-09)

Electrospray ionization is widely used to generate gas phase ions from a variety of molecules ranging from small ions to large proteins, while the ionization mechanism is claimed to depend on the size of the molecule. For small molecules, the

Global Trade Item Number

SKU	GTIN
D4072-25MG	04061832676524
D4072-5MG	04061832676531

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