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Merck
CN

D4546

7-Deacetylforskolin 7-hemisuccinate

≥98%

Synonym(s):

7β-O-Hemisuccinyl-1α,6β,9α-trihydroxy-8,13-epoxy-labd-14-en-11-one

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About This Item

Empirical Formula (Hill Notation):
C24H36O9
CAS Number:
Molecular Weight:
468.54
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
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SMILES string

[H][C@@]12[C@H](O)[C@H](OC(=O)CCC(O)=O)[C@@]3(C)O[C@](C)(CC(=O)[C@]3(O)[C@@]1(C)[C@@H](O)CCC2(C)C)C=C

assay

≥98%

storage temp.

−20°C

Application

Water-soluble derivative of forskolin which may be coupled to agarose for the purification of adenylate cyclase

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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E Pfeuffer et al.
Proceedings of the National Academy of Sciences of the United States of America, 82(10), 3086-3090 (1985-05-01)
The guanosine 5'-[beta, gamma-imido]triphosphate (p[NH]ppG)-activated adenylate cyclase from rabbit myocardial membranes was purified approximately equal to 60,000-fold to a specific activity of 15 mumol X mg-1 X min-1 by Lubrol PX extraction, affinity chromatography, and gel permeation HPLC. The major

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