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D5189

L-Asp-Asp-Rhodamine trifluoroacetate salt

Name: <SC>L</SC>-Asp-Asp-Rhodamine trifluoroacetate salt
Brand: SIGMA

>98%, solid

Synonym(s):

(L-Asp)₂ Rhodamine 110 ⋅ TFA

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About This Item

Empirical Formula (Hill Notation):

C₂₈H₂₄N₄O₉ · C₂HF₃O₂

Molecular Weight:

674.53

UNSPSC Code:

41106305

MDL number:

MFCD03452916

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Properties

assay

>98%

form

solid

storage temp.

−20°C

Description

Application

Substrate for detection of intracellular caspase activation by flow cytometry after apoptosis induction in intact hematopoietic cell lines.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number

071K1978

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Rhodamine 110-linked amino acids and peptides as substrates to measure caspase activity upon apoptosis induction in intact cells.

H Hug et al.

Biochemistry, 38(42), 13906-13911 (1999-10-21)

Caspases (cysteine aspartate-specific proteases) are a structurally related group of cysteine proteases that cleave peptide bonds following specific recognition sequences. They play a central role in activating apoptosis of vertebrate cells. To measure apoptosis induced by various stimuli and at