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Merck
CN

D5763

N-(2,4-Dinitroanilino)maleimide

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About This Item

Empirical Formula (Hill Notation):
C10H6N4O6
CAS Number:
Molecular Weight:
278.18
UNSPSC Code:
12352103
PubChem Substance ID:
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InChI

1S/C10H6N4O6/c15-9-3-4-10(16)12(9)11-7-2-1-6(13(17)18)5-8(7)14(19)20/h1-5,11H

InChI key

NBLHPQHLKDLIKS-UHFFFAOYSA-N

storage temp.

−20°C

pictograms

Skull and crossbones

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Regulatory Information

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S S Keskar et al.
The Biochemical journal, 281 ( Pt 3), 601-605 (1992-02-01)
The kinetics of chemical modification of the xylanase from a thermotolerant Streptomyces T7 indicated the involvement of 1 mol of cysteine residue/mol of enzyme [Keskar, Srinivasan & Deshpande (1989) Biochem. J. 261, 49-55]. The chromophoric reagent N-(2,4-dinitroanilino)maleimide (DAM) reacts covalently
M Rao et al.
The Biochemical journal, 316 ( Pt 3), 771-775 (1996-06-15)
N-(2,4-Dinitroanilino)maleimide (DAM) reacts covalently with the thiol group of the xylanase from Chainia leading to complete inactivation in a manner similar to N-ethylmaleimide, but provides a reporter group at the active site of the enzyme. Increasing amounts of xylan offered

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