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D6071

Diphenylacetohydroxamic acid

≥98% (HPLC)

Synonym(s):

N-Hydroxy diphenylacetamide

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About This Item

Empirical Formula (Hill Notation):
C14H13NO2
CAS Number:
4099-51-8
Molecular Weight:
227.26
NACRES:
NA.77
PubChem Substance ID:
329798821
UNSPSC Code:
12352202
MDL number:
MFCD16314231
Assay:
≥98% (HPLC)
Form:
powder
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assay

≥98% (HPLC)

form

powder

color

off-white to light tan

solubility

DMSO: >20 mg/mL

storage temp.

2-8°C

SMILES string

ONC(=O)C(c1ccccc1)c2ccccc2

InChI

1S/C14H13NO2/c16-14(15-17)13(11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10,13,17H,(H,15,16)

InChI key

OFSBBVCLWMCGNY-UHFFFAOYSA-N

Biochem/physiol Actions

Diphenylacetohydroxamic acid is a class IIa selective histone deacetylase inhibitor.

Features and Benefits

This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

pictograms

Exclamation markEnvironment
GHS07,GHS09

signalword

Warning

hcodes

H302,H400

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
050M4608V
050M4608

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Articles

Discover Bioactive Small Molecules for Gene Regulation

We offer a variety of small molecule research tools, such as transcription factor modulators, inhibitors of chromatin modifying enzymes, and agonists/antagonists for target identification and validation in gene regulation research; a selection of these research tools is shown below.

Douglas D Lemon et al.
FEBS letters, 589(10), 1080-1088 (2015-03-31)
PKD-mediated phosphorylation of class IIa HDACs frees the MEF2 transcription factor to activate genes that govern muscle differentiation and growth. Studies of the regulation and function of this signaling axis have involved MC1568 and Gö-6976, which are small molecule inhibitors

Global Trade Item Number

SKUGTIN
D6071-10MG04061832644929
D6071-50MG04061832270357