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D6375

2′-Deoxyadenosine 5′-monophosphate

Name: 2&#8242;-Deoxyadenosine 5&#8242;-monophosphate
Brand: SIGMA

98-100%, synthetic (organic), powder

Synonym(s):

2′-Deoxy-AMP, 2′-Deoxyadenylic acid, dAMP

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About This Item

Empirical Formula (Hill Notation):

C₁₀H₁₄N₅O₆P

CAS Number:

653-63-4

Molecular Weight:

331.22

UNSPSC Code:

41106305

eCl@ss:

32160414

PubChem Substance ID:

24894020

NACRES:

NA.51

EC Number:

211-503-1

MDL number:

MFCD00005753

Assay:

98-100%

Biological source:

synthetic (organic)

Form:

powder

Solubility:

1 N NH₄OH: 50 mg/mL, clear, colorless

Storage temp.:

−20°C

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Product Name

2′-Deoxyadenosine 5′-monophosphate, Sigma Grade, 98-100%

biological source

synthetic (organic)

Quality Level

200

grade

Sigma Grade

assay

98-100%

form

powder

solubility

1 N NH₄OH: 50 mg/mL, clear, colorless

storage temp.

−20°C

SMILES string

Nc1ncnc2n(cnc12)[C@H]3C[C@H](O)[C@@H](COP(O)(O)=O)O3

InChI

1S/C10H14N5O6P/c11-9-8-10(13-3-12-9)15(4-14-8)7-1-5(16)6(21-7)2-20-22(17,18)19/h3-7,16H,1-2H2,(H2,11,12,13)(H2,17,18,19)/t5-,6+,7+/m0/s1

InChI key

KHWCHTKSEGGWEX-RRKCRQDMSA-N

Related Categories

Phosphates

General description

N2′-Deoxyadenosine 5′-monophosphate is a nucleotide that serves as a building block for DNA synthesis.

Application

2’-deoxyadenosine-5’-monophosphatehas been used to study proteins via UV resonance Raman spectroscopy.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number

0000510336

0000515978

0000510337

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Toxic effects and DNA transformation

Savkovic S J

Journal of Separation Science, 6, 15-19 (2018)

Designed Antimicrobial Peptides for Topical Treatment of Antibiotic Resistant Acne Vulgaris.

Kathryn W Woodburn et al.

Antibiotics (Basel, Switzerland), 9(1) (2020-01-17)

Acne vulgaris, caused by the Gram-positive bacterium Cutibacterium acnes, is a prevalent dermatologic condition with substantial cutaneous and psychological morbidity. Mild acne is treated with topical antibiotics with more severe inflammatory forms requiring the prolonged use of oral antibiotics, resulting

High spatial resolution nanoslit SERS for single-molecule nucleobase sensing.

Chang Chen et al.

Nature communications, 9(1), 1733-1733 (2018-05-02)

Solid-state nanopores promise a scalable platform for single-molecule DNA analysis. Direct, real-time identification of nucleobases in DNA strands is still limited by the sensitivity and the spatial resolution of established ionic sensing strategies. Here, we study a different but promising

Photosensitization of 2'-deoxyadenosine-5'-monophosphate by pterin.

Gabriela Petroselli et al.

Organic & biomolecular chemistry, 5(17), 2792-2799 (2007-08-19)

UV-A radiation (320-400 nm) induces damages to the DNA molecule and its components through photosensitized reactions. Pterins, heterocyclic compounds widespread in biological systems, participate in relevant biological processes and are able to act as photosensitizers. We have investigated the photosensitization

Transition state analysis of acid-catalyzed dAMP hydrolysis.

Joe A B McCann et al.

Journal of the American Chemical Society, 129(22), 7055-7064 (2007-05-15)

Multiple kinetic isotope effects (KIEs) on deoxyadenosine monophosphate (dAMP) hydrolysis in 0.1 M HCl were used to determine the transition state (TS) structure and probe its intrinsic reactivity. The experimental KIEs revealed a stepwise (SN1) mechanism, with a discrete oxacarbenium

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Global Trade Item Number

SKU	GTIN
D6375-500MG	04061833006924
D6375-100MG	04061833006917
D6375-1G	04061826690598

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