D7389
Tiron
Synonym(s):
4,5-Dihydroxy-1,3-benzenedisulfonic acid disodium salt, Pyrocatechol-3,5-disulfonic acid disodium salt
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About This Item
Empirical Formula (Hill Notation):
C6H4Na2O8S2
CAS Number:
Molecular Weight:
314.20
EC Number:
205-741-5
UNSPSC Code:
12352103
MDL number:
Beilstein/REAXYS Number:
4629740
SMILES string
[Na+].[Na+].Oc1cc(cc(c1O)S([O-])(=O)=O)S([O-])(=O)=O
InChI
1S/C6H6O8S2.2Na/c7-4-1-3(15(9,10)11)2-5(6(4)8)16(12,13)14;;/h1-2,7-8H,(H,9,10,11)(H,12,13,14);;/q;2*+1/p-2
InChI key
ISWQCIVKKSOKNN-UHFFFAOYSA-L
Application
Cell permeable superoxide scavenger.
Other Notes
This product has been replaced by 172553-ALDRICH | 4,5-Dihydroxy-1,3-benzenedisulfonic acid disodium salt monohydrate, | (OH)2C6H2(SO3Na)2
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M T Watkins et al.
The Biochemical journal, 344 Pt 3, 747-754 (1999-12-10)
The experiments described in this paper were designed to determine the mechanism underlying the increase in 8-isoprostaglandin F(2alpha) (8-epi-PGF(2alpha)) production by cultured human endothelial cells during reoxygenation following hypoxia. Human umbilical artery endothelial cells were grown on microcarrier beads and
A N Ledenev et al.
Biochemistry international, 13(2), 391-396 (1986-08-01)
Tiron (1,2-dihydroxybenzene-3,5-disulfonate) is oxidized to an EPR-visible semiquinone by superoxide radicals produced by xanthine oxidase. The steady-state level of the Tiron radicals increases with an increased xanthine oxidase concentration. A calibration plot has been obtained relating the steady-state concentration of
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