D8691
2′, 3′-Dideoxyguanosine
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About This Item
Empirical Formula (Hill Notation):
C10H13N5O3
CAS Number:
Molecular Weight:
251.24
MDL number:
UNSPSC Code:
12352202
PubChem Substance ID:
form
solid
storage temp.
2-8°C
SMILES string
NC1=Nc2c(ncn2[C@H]3CC[C@@H](CO)O3)C(=O)N1
InChI
1S/C10H13N5O3/c11-10-13-8-7(9(17)14-10)12-4-15(8)6-2-1-5(3-16)18-6/h4-6,16H,1-3H2,(H3,11,13,14,17)/t5-,6+/m0/s1
InChI key
OCLZPNCLRLDXJC-NTSWFWBYSA-N
Application
Metacavir (6-O-methyl-2′, 3′-dideoxyguanosine) is a reverse transcriptase inhibitor with potent activity against hepatitis B virus (HBV); it is a prodrug that is activated in vivo by demethylation and conversion to 2′, 3′-dideoxyguanosine.
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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