D9006
Nε-Dansyl-L-lysine
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About This Item
Empirical Formula (Hill Notation):
C18H25N3O4S
CAS Number:
Molecular Weight:
379.47
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
InChI
1S/C18H25N3O4S/c1-21(2)16-10-5-8-14-13(16)7-6-11-17(14)26(24,25)20-12-4-3-9-15(19)18(22)23/h5-8,10-11,15,20H,3-4,9,12,19H2,1-2H3,(H,22,23)/t15-/m0/s1
SMILES string
[H][C@](N)(CCCCNS(=O)(=O)c1cccc2c(cccc12)N(C)C)C(O)=O
InChI key
VQPRNSWQIAHPMS-HNNXBMFYSA-N
application(s)
detection
storage temp.
−20°C
Biochem/physiol Actions
Nepsilon-Dansyl-L-lysine is used to study binding conformations of drugs to human serum albumin. Nepsilon-Dansyl-L-lysine is used as the template molecule to form molecularly imprinted monolayers (MIMs) useful to produce optical biosensor recognition elements
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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G M Humphries et al.
Biophysical journal, 42(3), 307-310 (1983-06-01)
Dansyl lysine (DL) is a fluorescent compound that has significantly higher solubility in synthetic phosphatidylcholine (PC) membranes with a low cholesterol content than it does in water or in membranes having a high cholesterol content. Its fluorescence intensity is enhanced
J M Mesaros et al.
Analytical chemistry, 65(22), 3313-3319 (1993-11-15)
Continuous zone electrophoretic separations in channels have been demonstrated. This new technique has the potential to continuously sample and separate analytes from volume-limited microenvironments. A small-bore capillary is used to electrophoretically sample, but not separate, a mixture of dansylated amino
G M Humphries et al.
The Journal of membrane biology, 80(3), 249-256 (1984-01-01)
Using mouse spleen cells, before and after treatment with glutaraldehyde or mild hyperthermia, we observe a strong correlation between permeability to fluorescein and susceptibility to staining with N epsilon-dansyl-L-lysine (irrespective of the cells' ability to exclude trypan blue). We observe
Nuclear magnetic resonance study of antibodies: a multinuclear approach.
Y Arata et al.
Methods in enzymology, 239, 440-464 (1994-01-01)
S Y Woo et al.
International journal of radiation oncology, biology, physics, 14(2), 361-365 (1988-02-01)
The heat response of five human tumor biopsies has been examined using the fluorescent probe dansyl lysine and multiparameter flow cytometry. Dansyl lysine has previously been shown to possess specificity for heat killed mammalian cells. The human tumors tested included
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