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Merck
CN

D9408

L-5,5-Dimethylthiazolidine-4-carboxylic acid

Synonym(s):

DTC

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About This Item

Empirical Formula (Hill Notation):
C6H11NO2S
CAS Number:
Molecular Weight:
161.22
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
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InChI

1S/C6H11NO2S/c1-6(2)4(5(8)9)7-3-10-6/h4,7H,3H2,1-2H3,(H,8,9)/t4-/m1/s1

SMILES string

CC1(C)SCN[C@@H]1C(O)=O

InChI key

PMQQFSDIECYOQV-SCSAIBSYSA-N

assay

≥98% (TLC)

form

powder

color

white

storage temp.

2-8°C

Biochem/physiol Actions

L-5,5-Dimethylthiazolidine-4-carboxylic acid (DTC) is used as a proline analog with restricted conformation in studies on receptor bound conformational requirements for agonists and antagonists of angiotensin II (ANG II).

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Aleksandra Siekierska et al.
Nature communications, 10(1), 708-708 (2019-02-14)
Aminoacyl tRNA synthetases (ARSs) link specific amino acids with their cognate transfer RNAs in a critical early step of protein translation. Mutations in ARSs have emerged as a cause of recessive, often complex neurological disease traits. Here we report an
Martin J Herrmann et al.
International journal of psychophysiology : official journal of the International Organization of Psychophysiology, 109, 21-28 (2016-09-30)
Emotional processing is probably the most crucial tool for orienting oneself in our everyday social life and has been considered to be highly automatic for a long time. Dual task (DT) research shows that information competing for working memory resources
Esther N Klein Hesselink et al.
Clinical biochemistry, 50(12), 696-702 (2017-03-01)
Chronic suppression of TSH in patients treated for differentiated thyroid carcinoma (DTC) may induce cardiac damage and increase risk for cardiovascular events and premature mortality. We aimed to compare circulating concentrations of N-terminal pro Brain Natriuretic Peptide (NT-proBNP) of DTC
B H-H Lang et al.
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 41(6), 758-765 (2015-02-15)
Rapid rise in differentiated thyroid cancer (DTC) may impose a heavy economic burden on future healthcare. We aimed to calculate the average first-year monetary cost/patient for DTC and estimate the projected cost burden on our local healthcare system. Medical records
Alasdair Formanuik et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 22(50), 17976-17979 (2016-10-28)
Improving our comprehension of diverse CO2 activation pathways is of vital importance for the widespread future utilization of this abundant greenhouse gas. CO2 activation by uranium(III) complexes is now relatively well understood, with oxo/carbonate formation predominating as CO2 is readily

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