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E000638

Adipic acid dihydrazide

Name: Adipic acid dihydrazide
Brand: SIGMA

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About This Item

Linear Formula:

NH₂NHCO(CH₂)₄CONHNH₂

CAS Number:

1071-93-8

Molecular Weight:

174.20

EC Number:

213-999-5

UNSPSC Code:

12352200

MDL number:

MFCD00007614

Beilstein/REAXYS Number:

973863

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mp

180-182 °C (lit.)

SMILES string

NNC(=O)CCCCC(=O)NN

InChI

1S/C6H14N4O2/c7-9-5(11)3-1-2-4-6(12)10-8/h1-4,7-8H2,(H,9,11)(H,10,12)

InChI key

IBVAQQYNSHJXBV-UHFFFAOYSA-N

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Physico-chemical properties of Salmonella typhi Vi polysaccharide-diphtheria toxoid conjugate vaccines affect immunogenicity.

So Jung An et al.

Vaccine, 29(44), 7618-7623 (2011-08-17)

In this study it was demonstrated that the immunogenicity of Vi polysaccharide-diphtheria toxoid conjugates was related to the physical and chemical structure of the conjugate. Conjugates were prepared in two steps, firstly binding adipic acid dihydrazide (ADH) spacer molecules to

Carbodiimide or periodate method to prepare peroxidase hydrazide for its use in immunoassay.

Tulsidas G Shrivastav

Journal of immunoassay & immunochemistry, 25(3), 295-304 (2004-10-06)

Peroxidase hydrazides were prepared by conjugating horseradish peroxidase (HRP) to adipic acid dihydrazide (ADH) by carbodiimide or periodate oxidation method. The resulting HRP hydrazides (ADH-HRP) were conjugated to cortisol-21-hemisuccinate (cortisol-21-HS) by forming diimide bonds using the N-hydroxysuccinimide (NHS) carbodiimide mediated

Substitution of carbonate buffer by water for IgG immobilization in enzyme linked immunosorbent assay.

Tulsidas G Shrivastav et al.

Journal of immunoassay & immunochemistry, 24(2), 191-203 (2003-06-05)

The first step of enzyme linked immunosorbent assay (ELISA), namely, adsorption of antigen or antibody to the plastic microtiter well plate, was studied as a function of insolubility of IgG in water. Immobilization efficiency was assessed in terms of number

In situ forming hydrogels composed of oxidized high molecular weight hyaluronic acid and gelatin for nucleus pulposus regeneration.

Yu-Chun Chen et al.

Acta biomaterialia, 9(2), 5181-5193 (2012-10-09)

Encapsulation of nucleus pulposus (NP) cells within in situ forming hydrogels is a novel biological treatment for early stage intervertebral disc degeneration. The procedure aims to prolong the life of the degenerating discs and to regenerate damaged tissue. In this

Glycan analysis by reversible reaction to hydrazide beads and mass spectrometry.

Shuang J Yang et al.

Analytical chemistry, 84(5), 2232-2238 (2012-02-07)

Investigation into glycoproteins and their associated glycans is the key to understanding the function of glycoproteins in biological pathways and disease development. Current methods for glycan analysis are generally based on multiple preparation processes to separate glycans from proteins and

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