Skip to Content
Merck
CN

E1636

Sigma-Aldrich

β-Estradiol 3,17-disulfate dipotassium salt

≥95%

Synonym(s):

1,3,5(10)-Estratriene 3,17β-disulfate, 3,17β-Dihydroxy-1,3,5(10)-estratriene disulfate

Sign Into View Organizational & Contract Pricing

About This Item

Linear Formula:
C18H22O8S2K2
CAS Number:
17046-60-5
Molecular Weight:
508.69
MDL number:
MFCD00058502
UNSPSC Code:
51111800
PubChem Substance ID:
24894425
NACRES:
NA.77
Biological source:
synthetic
Form:
powder
Assay:
≥95%

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

biological source

synthetic

Assay

≥95%

form

powder

technique(s)

inhibition assay: suitable

solubility

water: 50 mg/mL, clear, colorless

shipped in

ambient

storage temp.

−20°C

SMILES string

[K].[H][C@]12CC[C@]3(C)[C@H](CC[C@@]3([H])[C@]1([H])CCc4cc(OS(O)(=O)=O)ccc24)OS(O)(=O)=O

InChI

1S/C18H24O8S2.K.H/c1-18-9-8-14-13-5-3-12(25-27(19,20)21)10-11(13)2-4-15(14)16(18)6-7-17(18)26-28(22,23)24;;/h3,5,10,14-17H,2,4,6-9H2,1H3,(H,19,20,21)(H,22,23,24);;/t14-,15-,16+,17+,18+;;/m1../s1

InChI key

CPIZVUIARARPNO-LBARCDFESA-N

Biochem/physiol Actions

Among other effects, this conjugated estrogen selectively inhibits glutathione S-transferases.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

监管及禁止进口产品

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
BGBB6707V
078K37773
078K37772
078K37771
033H38382

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Angelo Quaranta et al.
PloS one, 4(11), e7699-e7699 (2009-11-06)
Dramatic declines in amphibian populations have been described all over the world since the 1980s. The evidence that the sensitivity to environmental threats is greater in amphibians than in mammals has been generally linked to the observation that amphibians are
Selective inhibition of glutathione S-transferases by 17 beta-estradiol disulfate.
V S Ohl et al.
Archives of biochemistry and biophysics, 180(1), 186-190 (1977-04-15)
J J Barycki et al.
Archives of biochemistry and biophysics, 345(1), 16-31 (1997-09-01)
3beta-(Iodoacetoxy)dehydroisoandrosterone (3beta-IDA), an analogue of the electrophilic substrate, Delta5-androstene-3,17-dione, as well as an analogue of several other steroid inhibitors of glutathione S-transferase, was tested as an affinity label of rat liver glutathione S-transferase, isozyme 1-1. A time-dependent loss of enzyme
J D Bain et al.
Steroids, 43(6), 603-619 (1984-06-01)
The efficiencies for estrogen conjugate hydrolysis were compared between enzyme hydrolysis, acid solvolysis and a new method, ammonolysis. Samples included: 1) crystalline 1,3,5(10)-estratriene-3, 17 beta-diol disulfate (estradiol 3,17-disulfate), 2) squirrel monkey urine collected following an intravenous injection of [2,4,6,7-H] 1,3,5(10)-estratriene-3,17
P Angerer et al.
Journal of the American College of Cardiology, 36(6), 1789-1796 (2000-11-25)
The study objective was to clarify in a randomized, controlled, observer-blind trial whether hormone replacement therapy (HRT) improves elastic properties of the common carotid artery in women with signs of subclinical atherosclerosis, especially in subgroups with increased risk, and whether
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service