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Merck
CN

E1906

Anti-EAPII (TTRAP) antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

Synonym(s):

Anti-ETS1-associated Protein 2, Anti-TRAF and TNF Receptor Associated Protein

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
MFCD08705452
Conjugate:
unconjugated
Clone:
polyclonal
Application:
western blot
Species reactivity:
human
Citations:
1
Technique(s):
western blot: 1:1,000-1:5,000

Key Documents

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Product Name

Anti-EAPII (TTRAP) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen ~41 kDa by calculation

species reactivity

human

technique(s)

western blot: 1:1,000-1:5,000

shipped in

dry ice

storage temp.

−20°C

Quality Level

200

Gene Information

human ... TTRAP(51567)

Application

Anti-EAPII (TTRAP) antibody produced in rabbit is suitable for western blot analysis at a working dilution of 1:1000-1:5000.

Biochem/physiol Actions

Ets proteins are a family of conserved sequence specific DNA-binding proteins. They function as transcription factors with roles in differentiation, lymphoid cell development, invasiveness, and angiogenesis. ETS1-associated protein II (EAPII) interacts with ETS1 and other Ets proteins (ETS2 and FLI1). EAPII is mainly localized to the nucleus of mammalian cells. EAPII negatively modulates the transcriptional activity of ETS1. It reduces synergistic transactivation by ETS1 and AP-1. Re-expression of EAPII prevents the migration of epithelial cancer cells. It does not affect cell viability.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Immunogen

peptide corresponding to the human EAPII (amino acids 11-28).

Physical form

Solution of 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide.

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Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
075K1307

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Huiping Pei et al.
Oncogene, 22(18), 2699-2709 (2003-05-14)
Ets proteins constitute a family of conserved sequence-specific DNA-binding proteins and function as transcription factors. ETS1 plays important roles in differentiation, lymphoid cell development, invasiveness and angiogenesis. Such diverse roles of ETS1 are likely to be dependent on its associated

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