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Merck
CN

E2145

Express-Ion™ exchanger D free base

60-130 μm

Synonym(s):

DEAE-Cellulose, Cellulose DEAE, Diethylaminoethyl-cellulose

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About This Item

CAS Number:
9013-34-7
UNSPSC Code:
47101511
PubChem Substance ID:
24894457
MDL number:
MFCD00146622

Key Documents

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InChI

1S/C12H22O11/c13-1-3-5(15)6(16)9(19)12(22-3)23-10-4(2-14)21-11(20)8(18)7(10)17/h3-20H,1-2H2/t3?,4?,5?,6?,7?,8?,9?,10-,11?,12+/m1/s1

SMILES string

OC[C@@H]1O[C@@H](O[C@H]2[C@@H](O)[C@H](O)[C@@H](O)O[C@H]2CO)[C@@H](O)[C@H](O)[C@H]1O

InChI key

GUBGYTABKSRVRQ-WFVLMXAXSA-N

matrix active group

DEAE (diethylaminoethyl)

particle size

60-130 μm

pH

2-9

capacity

1 meq/g

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Application

Express-Ion exchangers are weakly basic anion exchangers used in protein chromatography, ion exchange chromatography, cation exchange media, cellulose ion exchange TLC adsorbents and DEAE-cellulose anion exchange TLC adsorbents.

Legal Information

Express-Ion is a trademark of Whatman International Ltd.

Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
100M1764
118K1457
068K1220
057K1425
106K1872

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P R Levison et al.
Journal of chromatography. A, 890(1), 45-51 (2000-09-08)
A new technique in downstream processing, suspended bed chromatography has been developed. This hybrid technique exploiting the benefits of batch adsorption and the process advantages of an enclosed column system can be carried out using established contactors and adsorbents. A
G Denton et al.
Journal of chromatography. A, 908(1-2), 223-234 (2001-02-24)
The chromatography of the murine hybridoma cell C595/102 culture supernatant expressing the therapeutic monoclonal antibody C595, on the cation-exchange cellulose Whatman Express-Ion Exchanger S has been investigated. Initial method scouting studies using purified C595 in 1-ml mini columns demonstrated that
Tau Chuan Ling et al.
Journal of chromatography. A, 989(1), 109-118 (2003-03-19)
Suspended bed chromatography (SBC) is a new hybrid technique concomitantly benefiting from batch adsorption, the process advantages of an enclosed system, and its compatibility with established commercial chromatographic contactors and adsorbents. SBC was evaluated in the anion-exchange capture and chromatographic
Larry D Mesner et al.
Methods in molecular biology (Clifton, N.J.), 521, 121-137 (2009-07-01)
In order to perform 2-D gel analyses on restriction fragments from higher eukaryotic genomes, it is necessary to remove most of the linear, nonreplicating, fragments from the starting DNA preparation. This is so because the replication intermediates in a single-copy
Kazushi Imai et al.
Nature protocols, 3(7), 1111-1124 (2008-07-05)
Matrix metalloproteinases (MMPs) are zinc endopeptidases composed of 23 members in humans, which belong to a subfamily of the metzincin superfamily. They play important roles in many pathophysiological events including development, organogenesis, angiogenesis, tissue remodeling and destruction, and cancer cell
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