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Merck
CN

E2625

(+)-Pseudoephedrine

Synonym(s):

(+)-ψ-Ephedrine, (1S,2S)-2-Methylamino-1-phenyl-1-propanol, d-Isoephedrine, d-Pseudoephedrine

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About This Item

Empirical Formula (Hill Notation):
C10H15NO
CAS Number:
Molecular Weight:
165.23
EC Number:
202-018-6
UNSPSC Code:
41116107
MDL number:
Beilstein/REAXYS Number:
2414132
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grade

analytical standard

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

mp

118-120 °C

format

neat

SMILES string

CN[C@@H](C)[C@@H](O)c1ccccc1

InChI

1S/C10H15NO/c1-8(11-2)10(12)9-6-4-3-5-7-9/h3-8,10-12H,1-2H3/t8-,10+/m0/s1

InChI key

KWGRBVOPPLSCSI-WCBMZHEXSA-N

Application

(+)-Pseudoephedrine may be used as a reference standard in the determination of pseudoephedrine in pharmaceutical formulations using high performance thin layer chromatography (HPTLC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Non-selective adrenergic agonist; decongestant


pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

新产品

This item has



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Stability indicating HPTLC method for the simultaneous determination of pseudoephedrine and cetirizine in pharmaceutical formulations.
Makhija N S and Vavia R P.
Journal of Pharmaceutical and Biomedical Analysis, 25(3-4), 663-667 (2001)
Pablo Vazquez-Roig et al.
The Science of the total environment, 494-495, 49-57 (2014-07-17)
The enantiomeric and diastereomeric profiling of chiral pharmaceuticals (ephedrine, norephedrine, atenolol and venlafaxine) and illicit drugs (amphetamine, methamphetamine, 3,4-methylenedioxyamphetamine (MDA), 3,4-methylenedioxy-N-methylamphetamine (MDMA) and 3,4-methylenedioxy-N-ethylamphetamine (MDEA)) was undertaken over a period of fourteen consecutive days in three wastewater treatment plants (WWTPs)
Sian E Evans et al.
Analytica chimica acta, 882, 112-126 (2015-06-05)
This is the first study presenting a multi-residue method allowing for comprehensive analysis of several chiral pharmacologically active compounds (cPACs) including beta-blockers, antidepressants and amphetamines in wastewater and digested sludge at the enantiomeric level. Analysis of both the liquid and