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Merck
CN

E2632

2-Ethoxyethanol

~99% (GC)

Synonym(s):

Ethyl glycol, Ethylene glycol monoethyl ether

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About This Item

Linear Formula:
C2H5OCH2CH2OH
CAS Number:
Molecular Weight:
90.12
EC Number:
203-804-1
UNSPSC Code:
12190000
PubChem Substance ID:
Beilstein/REAXYS Number:
1098271
MDL number:
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InChI key

ZNQVEEAIQZEUHB-UHFFFAOYSA-N

InChI

1S/C4H10O2/c1-2-6-4-3-5/h5H,2-4H2,1H3

SMILES string

CCOCCO

vapor density

3.1 (vs air)

vapor pressure

3.8 mmHg ( 20 °C)

assay

~99% (GC)

autoignition temp.

460 °F

expl. lim.

14 %

refractive index

n20/D 1.407 (lit.)

mp

−90 °C (lit.)

density

0.93 g/mL at 25 °C (lit.)

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signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Flam. Liq. 3 - Repr. 1B

Storage Class

3 - Flammable liquids

wgk

WGK 2

flash_point_f

104.0 °F - closed cup

flash_point_c

40 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Regulatory Information

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Rui-Sheng Wang et al.
Industrial health, 45(4), 574-578 (2007-09-20)
Ethylene glycol monoethyl ether (EGEE) can cause damage to testes and sperm, and its metabolites are believed to play an important role in its toxicity. Aldehyde dehydrogenase 2 (ALDH2) is involved in the metabolism of this chemical. To investigate whether
Isaac A Adedara et al.
Human & experimental toxicology, 29(10), 801-812 (2010-02-23)
The effects of ethylene glycol monoethyl ether (EGEE) on the antioxidant systems of the testes and epididymal spermatozoa were investigated in rats at dose levels of 0, 100, 200 and 400 mg kg(-1) body weight (bw) administered orally by gavage
Chang Yong Yoon et al.
The Journal of veterinary medical science, 65(2), 207-212 (2003-03-26)
The effects of ethylene glycol monoethyl ether (EGEE) on testicular cell populations in rats were investigated by a flow cytometric method. Rats were administered by gavage with EGEE at the various doses of 0 (saline alone), 100, 200, 400, and
Douglas J Fort et al.
Drug and chemical toxicology, 25(3), 293-308 (2002-08-14)
Currently, no standardized and well-validated alternative models exist for screening for progesterone-responsive endocrine disrupting chemicals (EDCs). Because of this, a rapid assay for evaluating progestin/antiprogestin activity using Xenopus oocyte germinal vesicle breakdown (GVBD) as a model was evaluated. Five compounds
Gargi Bagchi et al.
International journal of andrology, 31(2), 269-274 (2008-01-09)
Methoxyacetic acid (MAA), the active biological oxidation product of the industrial solvent ethylene glycol monomethyl ether (EGME), causes acute toxicity in several species including humans. MAA primarily affects tissues with rapidly dividing cells and high rates of energy metabolism, including

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