E2781
Anti-Estrogen-Related Receptor α 1 antibody produced in rabbit
affinity isolated antibody, buffered aqueous solution
Synonym(s):
Anti-ERRα, Anti-ERR1, Anti-NR3B1
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About This Item
Conjugate:
unconjugated
Clone:
polyclonal
Application:
WB
Citations:
2
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen ~52 kDa (unidentified band is seen at ~37 kDa)
species reactivity
human, rat
technique(s)
western blot: 2 μg/mL using using COS-7 transfected cells
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
Gene Information
human ... ESRRA(2101)
Immunogen
synthetic peptide M(1)SSQVVGIEPLYIKAE(16) corresponding to amino acid residues 1-16 from human ERR1 protein.
Biochem/physiol Actions
Estrogen-Related Receptors (ERR) are hormone receptors that bind estrogen response elements that in turn bind specific DNA sequences and regulate transcription. Three ERRs are known, alpha, beta and gamma, with highly conserved ligand and DNA binding sequences. ERRα is selectively expressed in kidney, heart, cerebellum, intestine and skeletal muscle. It is an important modulator of energy balance, food intake, neuropeptide levels and response to stress.
Physical form
Provided as ~100 μg of affinity purified antibody (1 mg/mL) in phosphate buffered saline containing 1 mg/mL bovine serum albumin and 0.05% sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Related Content
Angie L Bookout et al.
Cell, 126(4), 789-799 (2006-08-23)
In multicellular organisms, the ability to regulate reproduction, development, and nutrient utilization coincided with the evolution of nuclear receptors (NRs), transcription factors that utilize lipophilic ligands to mediate their function. Studying the expression profile of NRs offers a simple, powerful
Mardi S Byerly et al.
BMC physiology, 13, 10-10 (2013-09-24)
Estrogen-related receptors (ERRs) are orphan nuclear hormone receptors expressed in metabolically active tissues and modulate numerous homeostatic processes. ERRs do not bind the ligand estrogen, but they are able to bind the estrogen response element (ERE) embedded within the ERR
Global Trade Item Number
| SKU | GTIN |
|---|---|
| E2781-100UG | 04061838070807 |