E3256
Edrophonium chloride
Synonym(s):
Ethyl(m-hydroxyphenyl)dimethylammonium chloride
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About This Item
Empirical Formula (Hill Notation):
C10H16ClNO
CAS Number:
Molecular Weight:
201.69
UNSPSC Code:
12352200
PubChem Substance ID:
EC Number:
204-138-4
MDL number:
SMILES string
[Cl-].CC[N+](C)(C)c1cccc(O)c1
InChI
1S/C10H15NO.ClH/c1-4-11(2,3)9-6-5-7-10(12)8-9;/h5-8H,4H2,1-3H3;1H
InChI key
BXKDSDJJOVIHMX-UHFFFAOYSA-N
Gene Information
human ... ACHE(43)
Biochem/physiol Actions
Acetycholinesterase inhibitor
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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James Rook et al.
Pediatric emergency care, 26(5), 374-375 (2010-05-11)
Myasthenia gravis is a rare, chronic, autoimmune disorder characterized by postsynaptic dysfunction at the neuromuscular junction. The disease affects more females than males. We describe the case of a 17-year-old female adolescent with recurrent episodes of dysarthria and dysphagia and
Chingmuh Lee et al.
Journal of critical care, 24(1), 43-49 (2009-03-11)
Although antiquated and long targeted for obsolescence, neostigmine and succinylcholine still serve the anesthesia community, decades after their inferior pharmacological profiles have been recognized. The need to quickly establish a good intubation condition with a relaxant that will recover rapidly
Yehonatan Sharabi et al.
Movement disorders : official journal of the Movement Disorder Society, 23(12), 1725-1732 (2008-07-29)
Patients with Parkinson's disease (PD) often have manifestations of autonomic failure. About 40% have neurogenic orthostatic hypotension (NOH), and among PD+NOH patients virtually all have evidence of cardiac sympathetic denervation; however, whether PD+NOH entails extra-cardiac noradrenergic denervation has been less