E3263
Efaroxan hydrochloride
≥98% (HPLC)
Synonym(s):
2-Ethyl-2-(imidazolin-2-yl)-2,3-dihydrobenzofuran hydrochloride, RX 821037A
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About This Item
Empirical Formula (Hill Notation):
C13H16N2O · HCl
CAS Number:
Molecular Weight:
252.74
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Quality Segment
assay
≥98% (HPLC)
solubility
H2O: >20 mg/mL
SMILES string
Cl.CCC1(Cc2ccccc2O1)C3=NCCN3
InChI
1S/C13H16N2O.ClH/c1-2-13(12-14-7-8-15-12)9-10-5-3-4-6-11(10)16-13;/h3-6H,2,7-9H2,1H3,(H,14,15);1H
InChI key
DWOIUCRHVWIHAH-UHFFFAOYSA-N
Gene Information
human ... ADRA1A(148), ADRA1B(147), ADRA1D(146), ADRA2A(150), ADRA2B(151), ADRA2C(152)
Biochem/physiol Actions
(+)-Isomer is a selective α-adrenoceptor antagonist; (−)-isomer is an imidazoline ligand that induces insulin secretion, mediated by the blockade of ATP-sensitive potassium channels in pancreatic β cells; I1 imidazoline binding site antagonist.
(+)-Isomer is a selective α-adrenoceptor antagonist; (−)-isomer is an imidazoline ligand; I1 imidazoline binding site antagonist.
Features and Benefits
This compound is featured on the Imidazoline Binding Sites and Potassium Channels pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
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