E6386
γ-Endorphin
≥95% (HPLC)
Synonym(s):
β-Lipotropin 61-77
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About This Item
Empirical Formula (Hill Notation):
C83H131N19O27S
CAS Number:
Molecular Weight:
1859.10
UNSPSC Code:
12352200
MDL number:
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Biochem/physiol Actions
Opioid agonist that does not produce generalized rigidity or loss of tail pinch reflex when injected intraventricularly.
Other Notes
β-Lipotropin fragment found in intermediate and anterior lobes of the pituitary
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
涉药品监管产品
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R D Voyksner et al.
Biomedical & environmental mass spectrometry, 18(10), 897-903 (1989-10-01)
High-performance liquid chromatography/thermospray mass spectrometry (HPLC/MS) was evaluated and optimized for the determination of beta- and gamma-endorphin. Thermospray spectra for the endorphins could be acquired under ion evaporation conditions, when a low vaporizor temperature (94 degrees C) and high source
Inhibition of contractile activity of rat cardiomyocytes in culture by alpha- and gamma-endorphins.
N A Sokolova et al.
Biomedical science, 2(2), 200-201 (1991-01-01)
J M Van Ree et al.
European journal of pharmacology, 279(2-3), 187-196 (1995-06-12)
To investigate the significance of endogenous, neuroleptic-like gamma-type endorphins and their putative receptors, polyclonal and monoclonal antibodies against gamma-type endorphins, which may bio-inactivate the ligands for the receptors, and monoclonal anti-idiotype antibodies, which presumably bind to the receptors, were injected
S A Martin-Moe et al.
Peptide research, 8(2), 70-76 (1995-03-01)
The possibility that hydrophobic interactions may be used as a basis for the design of receptor mimetic peptides for small peptide hormones that lack the potential to adopt amphiphilic secondary structures was tested by designing and characterizing receptor mimetic peptides
E A Young et al.
European journal of pharmacology, 167(2), 229-236 (1989-08-22)
With a number of acute stressors beta-endorphin is released into plasma. It is unclear if beta-endorphin is converted into any other biologically active products, nor is it clear if the rate or pathways of degradation are changed during chronic stress.
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