E6386
γ-Endorphin
≥95% (HPLC)
Synonym(s):
β-Lipotropin 61-77
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About This Item
Empirical Formula (Hill Notation):
C83H131N19O27S
CAS Number:
Molecular Weight:
1859.10
MDL number:
UNSPSC Code:
12352200
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Amino Acid Sequence
Tyr-Gly-Gly-Phe-Met-Thr-Ser-Glu-Lys-Ser-Gln-Thr-Pro-Leu-Val-Thr-Leu
Biochem/physiol Actions
Opioid agonist that does not produce generalized rigidity or loss of tail pinch reflex when injected intraventricularly.
Other Notes
β-Lipotropin fragment found in intermediate and anterior lobes of the pituitary
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
涉药品监管产品
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R D Voyksner et al.
Biomedical & environmental mass spectrometry, 18(10), 897-903 (1989-10-01)
High-performance liquid chromatography/thermospray mass spectrometry (HPLC/MS) was evaluated and optimized for the determination of beta- and gamma-endorphin. Thermospray spectra for the endorphins could be acquired under ion evaporation conditions, when a low vaporizor temperature (94 degrees C) and high source
Inhibition of contractile activity of rat cardiomyocytes in culture by alpha- and gamma-endorphins.
N A Sokolova et al.
Biomedical science, 2(2), 200-201 (1991-01-01)
S A Martin-Moe et al.
Peptide research, 8(2), 70-76 (1995-03-01)
The possibility that hydrophobic interactions may be used as a basis for the design of receptor mimetic peptides for small peptide hormones that lack the potential to adopt amphiphilic secondary structures was tested by designing and characterizing receptor mimetic peptides
J M Van Ree et al.
European journal of pharmacology, 279(2-3), 187-196 (1995-06-12)
To investigate the significance of endogenous, neuroleptic-like gamma-type endorphins and their putative receptors, polyclonal and monoclonal antibodies against gamma-type endorphins, which may bio-inactivate the ligands for the receptors, and monoclonal anti-idiotype antibodies, which presumably bind to the receptors, were injected
K Hagi et al.
Blood, 86(4), 1316-1321 (1995-08-15)
The present study was performed to investigate the effect of beta-endorphin on macrophage colony-stimulating factor (M-CSF)-induced differentiation of macrophages from bone marrow cells in a semisolid culture system. beta-endorphin increased the number of macrophage colonies when bone marrow cells were
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