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E6902

Elastin, soluble from human aorta

lyophilized powder

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About This Item

CAS Number:
9007-58-3
UNSPSC Code:
12352202
EC Number:
232-701-4
MDL number:
MFCD02687373
Form:
lyophilized powder
Biological source:
human aorta

Key Documents

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InChI key

DPUYCSDGMSDKKV-MKBYFEBXSA-N

InChI

1S/C27H48N6O6/c1-9-17(6)23(32-24(36)19(13-15(2)3)30-18(7)34)26(38)29-14-21(35)31-22(16(4)5)27(39)33-12-10-11-20(33)25(37)28-8/h15-17,19-20,22-23H,9-14H2,1-8H3,(H,28,37)(H,29,38)(H,30,34)(H,31,35)(H,32,36)/t17-,19-,20-,22-,23-/m0/s1

biological source

human aorta

form

lyophilized powder

technique(s)

cell culture | mammalian: suitable

impurities

salt, free

UniProt accession no.

P15502

storage temp.

2-8°C

Quality Level

100

Gene Information

human ... ELN(2006)

Biochem/physiol Actions

Elastin, along with fibrillin, is responsible for the elastic properties of skin and arteries. Reported inhibitor of Clostridial collagenase.
Reported inhibitor of Clostridial collagenase

Preparation Note

Prepared from E6777 using the method of Partrige, et al.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

高风险级别生物产品--人源产品
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Certificates of Analysis (COA)

Lot/Batch Number
MKCV2224
MKCS4319
MKCS7992
MKCS6235
MKCP7397

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Jinzhi Li et al.
BMC cancer, 20(1), 217-217 (2020-03-17)
Colorectal cancer (CRC) is the most common cancer and a leading cause of death worldwide. Extracellular matrix (ECM) proteins regulate tumor growth and development in CRC. Elastin (ELN) is a component of ECM proteins involved in the tumor microenvironment. However
E H Sage et al.
Advances in experimental medicine and biology, 79, 291-312 (1977-01-01)
The aortae of a number of vertebrates and invertebrates were tested for the presence of elastin to determine when this protein first appears phylogenetically. Using several criteria, including amino acid composition, presence of desmosines, and histological characteristics, we found that
Hui Li et al.
Journal of anatomy, 236(1), 171-179 (2019-08-31)
Distinguishing arteries from veins in vivo has a great significance in clinical practices and preclinical studies. Optical imaging methods such as two-photon microscopy can provide high-resolution morphological information of tissue and are therefore extremely suitable for imaging small blood vessels.
Aleksandra Kuzan et al.
Folia histochemica et cytobiologica, 59(1), 8-21 (2021-02-10)
Extracellular matrix (ECM) proteins have been associated with atherosclerotic complications, such as plaque rupture, calcification and aneurysm. It is not clear what role different types of collagen play in the pathomechanism of atherosclerosis. The aim of the study was to
The chemistry of connective tissues. 2. Soluble proteins derived from partial hydrolysis of elastin.
S M PARTRIDGE et al.
The Biochemical journal, 61(1), 11-21 (1955-09-01)
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