E7138
Ethosuximide
T-type calcium channel antagonist
Synonym(s):
2-Ethyl-2-methylsuccinimide
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
About This Item
Empirical Formula (Hill Notation):
C7H11NO2
CAS Number:
Molecular Weight:
141.17
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352111
EC Number:
201-048-7
MDL number:
eCl@ss:
32150917
Product Name
Ethosuximide,
Quality Segment
solubility
ethanol: 100 mg/mL
SMILES string
O=C1NC(CC1(C)CC)=O
InChI
1S/C7H11NO2/c1-3-7(2)4-5(9)8-6(7)10/h3-4H2,1-2H3,(H,8,9,10)
InChI key
HAPOVYFOVVWLRS-UHFFFAOYSA-N
Gene Information
human ... CACNA1G(8913), CACNA1H(8912), CACNA1I(8911)
Application
Ethosuximide has been used:
- to confirm its effect on spike wave discharges (SWD) in rats
- to examine its effects on spontaneous locomotion and anxiety-related thigmotaxis behaviours in zebrafish larvae of wild type
- as a model drug for the treatment of epilepsy in vivo(4)
Biochem/physiol Actions
Ethosuximide is an anticonvulsant drug and an antagonist for T-type calcium channel. It is known to prevent spike wave discharges, characterized in absence seizures.
Features and Benefits
This compound is featured on the Calcium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Still not finding the right product?
Explore all of our products under Ethosuximide
Signal Word
Warning
Hazard Codes
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
PPE (personal protective equipment)
dust mask type N95 (US), Eyeshields, Gloves
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.