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E8000

Etiocholan-3α-ol-17-one glucuronide

Synonym(s):

3α-Hydroxy-5β-androstan-17-one 3-glucuronide, 5β-Androstan-3α-ol-17-one 3-glucuronide

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About This Item

Empirical Formula (Hill Notation):
C25H38O8
CAS Number:
3602-09-3
Molecular Weight:
466.56
UNSPSC Code:
12352200
PubChem Substance ID:
24894662
MDL number:
MFCD00067126
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form

solid

drug control

regulated under CDSA - not available from Sigma-Aldrich Canada

shipped in

ambient

storage temp.

−20°C

SMILES string

CC12CCC(CC1CCC3C2CCC4(C)C3CCC4=O)OC5OC(C(O)C(O)C5O)C(O)=O

InChI

1S/C25H38O8/c1-24-9-7-13(32-23-20(29)18(27)19(28)21(33-23)22(30)31)11-12(24)3-4-14-15-5-6-17(26)25(15,2)10-8-16(14)24/h12-16,18-21,23,27-29H,3-11H2,1-2H3,(H,30,31)

InChI key

VFUIRAVTUVCQTF-UHFFFAOYSA-N

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
010H3843

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P Boudou et al.
The Journal of clinical endocrinology and metabolism, 80(12), 3489-3493 (1995-12-01)
Hypothalamic-pituitary gonadal function is commonly altered in dialysis patients. Even though an improvement in general status and well-being has been noted after recombinant human erythropoietin supplementation, no significant changes were observed in the sex hormone profile. Pituitary gonadal axis as
V A Giagulli et al.
Clinical endocrinology, 36(6), 553-558 (1992-06-01)
The aim of the study was to investigate whether the absence of increased 5 alpha-reductase activity explained the absence of hirsutism in premenopausal obese women with increased free testosterone (FT) levels. As in hyperandrogenicity there generally exists evidence for increased
Fernand Labrie et al.
The Journal of steroid biochemistry and molecular biology, 110(1-2), 1-9 (2008-03-25)
Healthy postmenopausal women aged 60-65 years (n=150) were randomized to receive twice daily application on the skin of 3g of a 0.3% dehydroepiandrosterone (DHEA) or placebo emulsion for 12 months. Serum DHEA and eleven of its metabolites were measured at
D M Duffy et al.
Fertility and sterility, 64(4), 736-739 (1995-10-01)
To compare the peripheral versus the splanchnic contribution to the formation of 3 alpha-diol G. Prospective study in various groups of women and men. Reproductive Endocrine service of our University Medical Center. Six normal ovulatory women, five hirsute women with
B Lavallée et al.
Clinical endocrinology, 46(1), 93-100 (1997-01-01)
Insulin was found to decrease the concentration of serum dehydroepiandrosterone (DHEA) and DHEA-sulphate (DHEAS) and recent data suggest that an increase in the metabolic clearance rate of DHEA (MCRDHEA) may be involved. In this study, we have investigated the effects
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