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Merck
CN

E8277

EphA4/Fc Chimera from mouse

>95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder

Synonym(s):

Cek8, Hek8, Sek, Sek1, Tyro1

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About This Item

UNSPSC Code:
51111800
MDL number:
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biological source

mouse

recombinant

expressed in NSO cells

assay

>95% (SDS-PAGE)

form

lyophilized powder

mol wt

monomer calculated mol wt 85.7 kDa, ~110 kDa by SDS-PAGE (reducing)

storage condition

avoid repeated freeze/thaw cycles

impurities

endotoxin, tested

UniProt accession no.

storage temp.

−20°C

Gene Information

mouse ... Epha4(13838)

General description

Extracellular domain of mouse EphA4 (amino acids 1-547) fused to the C-terminal 6X histidine-tagged Fc region of human IgG1 via a polypeptide linker.

Biochem/physiol Actions

Member of the Eph receptor tyrosine kinase family shown to bind ephrin-A1, ephrin-A2, ephrin-A3, ephrin-A4, ephrin-A5, ephrin-B2, and ephrin-B3; involved in pattern formation and morphogenesis. EphA4 can be detected in B cells, T cells, and keratinocytes.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline.

Analysis Note

The biological activity is measured by its ability to bind recombinant human ephrin-A5 in an ELISA assay.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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