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Merck
CN

E9152

Eotaxin-2 from mouse

>95% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder

Synonym(s):

CCL24, MPIF-2

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About This Item

UNSPSC Code:
51111800
MDL number:
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biological source

mouse

recombinant

expressed in E. coli

assay

>95% (SDS-PAGE)

form

lyophilized powder

potency

0.2-0.8 mg per mL ED50

mol wt

predicted mol wt ~10.6 kDa

storage condition

avoid repeated freeze/thaw cycles

impurities

endotoxin, tested

UniProt accession no.

storage temp.

−20°C

Gene Information

mouse ... Ccl24(56221)

Biochem/physiol Actions

Eotaxin-2 is a potent eosinophil chemotactic factor, which is involved in homeostatic, allergen-induced, and IL-4 related immune responses. Eotaxin-2 exhibits 40%, 42%, and 39% amino acid identity to MCP-3, MIP-1α, and eotaxin, respectively. Mature mouse and human eotaxin-2 share approximately 57% amino acid sequence identity.
Potent eosinophil chemotactic factor, which is involved in homeostatic, allergen-induced, and IL-4 related immune responses.

Physical form

Lyophilized from a 0.2 μm filtered solution in 30% acetonitrile and 0.1% TFA containing 1.25 mg bovine serum albumin.

Analysis Note

The biological activity is measured by its ability to induce chemotaxis of rat Y3 cells transfected with the CCR3 receptor.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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