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E9895

[D-Val22]-Big endothelin 1 fragment 16-38

≥95% (HPLC)

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About This Item

Empirical Formula (Hill Notation):
C119H180N32O33
CAS Number:
158884-64-1
Molecular Weight:
2586.90
UNSPSC Code:
12352200
MDL number:
MFCD00672419
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assay

≥95% (HPLC)

composition

Peptide content, ~70%

storage temp.

−20°C

Biochem/physiol Actions

Antagonist of big endothelin 1-mediated dopamine release.

Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
039H0921
026H0663
026H06631
018H0365
018H03651

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A Morita et al.
FEBS letters, 353(1), 84-88 (1994-10-10)
Endothelin converting enzyme (ECE) is essential for generation of the biological effects of endothelin-1 (ET-1) from a precursor, big endothelin-1 (Big ET-1). We synthesized four analogs of human Big ET-1[16-38], substituted with single D-amino acids at P1, P2, P1' and