F0393
2′-Fucosyl-D-lactose
from human milk, ≥98% (HPAE/PAD)
Synonym(s):
α-L-Fuc-(1→2)-β-D-Gal-(1→4)-D-Glc
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About This Item
Empirical Formula (Hill Notation):
C18H32O15
CAS Number:
Molecular Weight:
488.44
UNSPSC Code:
12352201
PubChem Substance ID:
MDL number:
biological source
human milk
assay
≥98% (HPAE/PAD)
form
powder
solubility
H2O: 2 mg + 0.2 mL, clear, colorless
storage temp.
2-8°C
SMILES string
C[C@@H]1O[C@H](O[C@@H]2[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]2O[C@H]3[C@H](O)[C@@H](O)C(O)O[C@@H]3CO)[C@@H](O)[C@H](O)[C@@H]1O
InChI
1S/C18H32O15/c1-4-7(21)9(23)13(27)17(29-4)33-15-10(24)8(22)5(2-19)31-18(15)32-14-6(3-20)30-16(28)12(26)11(14)25/h4-28H,2-3H2,1H3/t4-,5+,6+,7+,8-,9+,10-,11+,12+,13-,14+,15+,16?,17+,18-/m0/s1
InChI key
SNFSYLYCDAVZGP-ZTFPOLCTSA-N
Application
2′-Fucosyl-D-lactose is used as substrate to identify, differentiate and characterize fucosidases. It is also used in the development of biosensors to identify anti-infective oligosaccharides. 2′-Fucosyl-D-lactose is used to differentiate IL-8 receptor specificity and function. It may be used to study is effects on intestinal microbiota and as a reference compound in assays developed to detect and measure milk sugars.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
涉药品监管产品
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Zhuo-Teng Yu et al.
Glycobiology, 23(2), 169-177 (2012-10-03)
Breast-fed infant microbiota is typically rich in bifidobacteria. Herein, major human milk oligosaccharides (HMOS) are assessed for their ability to promote the growth of bifidobacteria and to acidify their environment, key features of prebiotics. During in vitro anaerobic fermentation of
Myriam Coulet et al.
Regulatory toxicology and pharmacology : RTP, 68(1), 59-69 (2013-11-23)
In order to match the composition of human breast milk more closely, it is now possible to supplement commercial infant formula (IF) with synthesised oligosaccharides that are chemically identical to human milk oligosaccharides. The safety data generated on a new
C Campbell et al.
Cell, 35(1), 303-309 (1983-11-01)
Two rare and dominant mutants of Chinese hamster ovary (CHO) cells, LEC11 and LEC12, express the mouse embryonic antigen SSEA-1. Parental CHO cells and the revertants, LEC11.R9 and LEC12.R10, do not express this antigen as detected by a sensitive radioimmunoassay