F1428
Fenvalerate
≥97%
Synonym(s):
α-Cyano-3-phenoxybenzyl α-(4-chlorophenyl)isovalerate
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About This Item
Empirical Formula (Hill Notation):
C25H22ClNO3
CAS Number:
Molecular Weight:
419.90
UNSPSC Code:
12352200
NACRES:
NA.77
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
2025982
Assay:
≥97%
Quality Segment
assay
≥97%
storage temp.
−20°C
SMILES string
CC(C)C(C(=O)OC(C#N)c1cccc(Oc2ccccc2)c1)c3ccc(Cl)cc3
InChI
1S/C25H22ClNO3/c1-17(2)24(18-11-13-20(26)14-12-18)25(28)30-23(16-27)19-7-6-10-22(15-19)29-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3
InChI key
NYPJDWWKZLNGGM-UHFFFAOYSA-N
General description
Fenvalerate an ester molecule, exists in four stereoisomers with two chiral centers.
Application
Fenvalerate has been used to study the effect of Fen exposure on reproductive functions.
Biochem/physiol Actions
Fenvalerate has good insecticidal potential and is less toxic to animals. It might cause endocrine disruption and reproductive dysfunction in humans. Metabolism of fenvalerate includes oxidation, ester cleavage and conjugation reaction. It is stable at pH 5 and 7, while it gets hydrolyzed at pH 9. In rat models it is found to hinder the action of mitochondrial enzymes.
Fenvalerate is a type II semi-synthetic pyrethrin, which acts as a potent inhibitor of calcineurin (protein phosphatase 2B). This inhibitory action results in cellular hyperexcitability by causing non-mutated calcium channels to remain open for an extended period of time allowing an abundance of Ca2+ to enter the cell.
Type II pyrethroid. Potent inhibitor of calcineurin (protein phosphatase 2B).
Preparation Note
Fenvalerate has been reported to be soluble in DMSO, ethanol, and acetone.
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signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| F1428-25MG | 04061833270936 |