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F3764

Furegrelate sodium salt

Name: Furegrelate sodium salt
Brand: SIGMA

Synonym(s):

5-(3-Pyridinylmethyl)benzofurancarboxylic acid sodium-potassium salt

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About This Item

Empirical Formula (Hill Notation):

C₁₅H₁₀NNaO₃

CAS Number:

85666-17-7

Molecular Weight:

275.23

UNSPSC Code:

12352200

MDL number:

MFCD00058448

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Properties

storage temp.

−20°C

SMILES string

[Na+].[O-]C(=O)c1cc2cc(Cc3cccnc3)ccc2o1

Gene Information

human ... TBXAS1(6916)

Description

Biochem/physiol Actions

Thromboxane synthetase inhibitor.

Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

188.6 °F - Solvent

flash_point_c

87 °C - Solvent

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Inhibition of platelet thromboxane A2 synthase activity by sodium 5-(3'-pyridinylmethyl)benzofuran-2-carboxylate.

R R Gorman et al.

Prostaglandins, 26(2), 325-342 (1983-08-01)

This report outlines the activity of a new thromboxane synthase inhibitor sodium, 5-(3-pyridinylmethyl)-2-benzofurancarboxylate, (U-63557A). U-63557A is a potent inhibitor of the thromboxane synthase in human platelets in vitro, as well as in rhesus monkey platelets ex vivo. A single oral