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Merck
CN

F7049

Fibronectin Fragment 1977-1991

≥97% (HPLC)

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About This Item

Empirical Formula (Hill Notation):
C74H133N25O23
Molecular Weight:
1741.00
UNSPSC Code:
12352200
MDL number:
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SMILES string

CC[C@H](C)[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](N)CCCCN)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(O)=O

assay

≥97% (HPLC)

UniProt accession no.

storage temp.

−20°C

Gene Information

human ... FN1(2335)

Biochem/physiol Actions

Mediates cell adhesion; promotes neuronal adhesion and neurite outgrowth. Binds to the cell surface heparan sulfate proteoglycan (HSPG).

Other Notes

Peptide derived from the C-terminal heparin-binding domain of fibronectin.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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S L Drake et al.
The Journal of biological chemistry, 268(21), 15859-15867 (1993-07-25)
FN-C/H II (KNNQKSEPLIGRKKT), a heparin-binding peptide derived from the COOH-terminal heparin-binding domain of fibronectin, mediates cell adhesion for a variety of cell types and promotes neurite outgrowth. By systematic amino acid substitution of synthetic peptide analogues of FN-C/H II, the

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