F7049
Fibronectin Fragment 1977-1991
≥97% (HPLC)
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About This Item
Empirical Formula (Hill Notation):
C74H133N25O23
Molecular Weight:
1741.00
UNSPSC Code:
12352200
MDL number:
assay
≥97% (HPLC)
UniProt accession no.
storage temp.
−20°C
SMILES string
CC[C@H](C)[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](N)CCCCN)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(O)=O
Gene Information
human ... FN1(2335)
Biochem/physiol Actions
Mediates cell adhesion; promotes neuronal adhesion and neurite outgrowth. Binds to the cell surface heparan sulfate proteoglycan (HSPG).
Other Notes
Peptide derived from the C-terminal heparin-binding domain of fibronectin.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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S L Drake et al.
The Journal of biological chemistry, 268(21), 15859-15867 (1993-07-25)
FN-C/H II (KNNQKSEPLIGRKKT), a heparin-binding peptide derived from the COOH-terminal heparin-binding domain of fibronectin, mediates cell adhesion for a variety of cell types and promotes neurite outgrowth. By systematic amino acid substitution of synthetic peptide analogues of FN-C/H II, the