synthetic peptide corresponding to amino acids 544-560 of human FBI-1/Pokemon, conjugated to KLH.

Anti-FBI-1/Pokemon antibody is suitable for immunoprecipitation at a concentration of 2-4μL using A431 cell lysates and western blot (chemiluminescent) at a dilution of 1:4,000-1:6,000 using K-562 lysates.

FBI-1/Pokemon is a BTB/POZ containing zinc-finger protein. It is predominantly expressed in a subset of T-cell lymphoma and B-cell lymphomas. It is also found in breast, lung, colon, prostate, and bladder carcinomas. It has capacity to bind the HIV-inducer of short transcripts (IST), thus called FBI-1. It was identified as a critical factor in oncogenesis and was called Pokemon (POK erythroid myeloid ontogenic factor). By binding to the tumor suppressor gene ARF, the Pokemon exerts its oncogenic activity.

Solution in 0.01 M phosphate buffered saline, pH 7.4, and 15 mM sodium azide.

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