G1049
Poly-L -γ- glutamic acid sodium salt
suitable for drug transporter assays, Mol wt ≥750,000
Synonym(s):
γ-PGA
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About This Item
Product Name
Poly-
form
powder
Quality Segment
mol wt
≥750,000
technique(s)
drug transporter assay: suitable
color
white to off-white
application(s)
cell analysis
storage temp.
−20°C
Application
High molecular weight poly-γ-glutamic acid (γPGA) was found to increase levels of NK cell-mediated cytotoxicity and INF-γ secretion in C57BL/6 mice. Biodegradable γ-PGA nanoparticles have been evaluated for use as antigen delivery carriers and delivery of influenza virus hemagglutin (HA) vaccine. Additional life science applications for γ-PGA include uses in biodegradable fibers and nanofiber sheets, hydrogels, and cryoprotectants.
Other Notes
High molecular weight poly-γ-glutamic acid is a polymer of glutamic acid connected by amide linkages between α-amino and γ-carboxylic acid groups. γ-PGA is produced by fermentation in Bacillus species. The subunits are predominantly L -isomer.
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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