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Merck
CN

G1278

Sigma-Aldrich

Galantide

≥90% (HPLC)

Synonym(s):

M15

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About This Item

Empirical Formula (Hill Notation):
C104H151N25O26S
CAS Number:
138579-66-5
Molecular Weight:
2199.53
MDL number:
MFCD00144384
UNSPSC Code:
12352200
PubChem Substance ID:
329799835
NACRES:
NA.26

Key Documents

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Assay

≥90% (HPLC)

form

powder

technique(s)

drug transporter assay: suitable

color

white

UniProt accession no.

P22466

storage temp.

−20°C

SMILES string

CSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]3CCCN3C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc4ccc(O)cc4)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc5c[nH]c6ccccc56)NC(=O)CN)[C@@H](C)O)C(N)=O

InChI

1S/C104H151N25O26S/c1-54(2)39-70(91(142)113-52-87(139)129-37-20-27-80(129)103(154)120-69(33-35-82(107)134)93(144)119-68(32-34-81(106)133)94(145)124-76(44-61-23-16-13-17-24-61)99(150)123-74(43-60-21-14-12-15-22-60)92(143)112-51-86(138)116-71(40-55(3)4)95(146)118-67(89(109)140)36-38-156-11)121-96(147)72(41-56(5)6)122-98(149)75(45-62-28-30-64(132)31-29-62)117-85(137)50-111-90(141)58(9)114-102(153)79(53-130)127-100(151)78(47-83(108)135)125-97(148)73(42-57(7)8)126-104(155)88(59(10)131)128-101(152)77(115-84(136)48-105)46-63-49-110-66-26-19-18-25-65(63)66/h12-19,21-26,28-31,49,54-59,67-80,88,110,130-132H,20,27,32-48,50-53,105H2,1-11H3,(H2,106,133)(H2,107,134)(H2,108,135)(H2,109,140)(H,111,141)(H,112,143)(H,113,142)(H,114,153)(H,115,136)(H,116,138)(H,117,137)(H,118,146)(H,119,144)(H,120,154)(H,121,147)(H,122,149)(H,123,150)(H,124,145)(H,125,148)(H,126,155)(H,127,151)(H,128,152)/t58-,59+,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,88-/m0/s1

InChI key

TZOJVPDIYKRJSM-GKPUQKAJSA-N

Gene Information

human ... GAL(51083)

Amino Acid Sequence

Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2

Biochem/physiol Actions

Galanin receptor antagonist
Galanin, a neuropeptide, mediates its physiological effects through three G protein-coupled receptor (GCPR) subtypes, GalR1, GalR2, and GalR3. Galantide, C7, M35, and M40 are Galanin receptor antagonists used to differentiate and characterize Galanin receptor signaling pathways that impact processes such as acute pancreatitis.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
071M1826V
041M1399V
011M1902V
019K1307
048K1464

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