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G1296

Sigma-Aldrich

Glycitin

≥98% (HPLC)

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Synonym(s):
4′,7-Dihydroxy 6-methoxyisoflavone 7-O-glucoside, 4H-1-Benzopyran-4-one, 7-(β-D-glucopyranosyloxy)-3-(4-hydroxyphenyl)-6-methoxy-, Glycitein 7-O-β-glucoside
Empirical Formula (Hill Notation):
C22H22O10
CAS Number:
40246-10-4
Molecular Weight:
446.40
MDL number:
MFCD00800711
NACRES:
NA.25

biological source

plant (Pueraria thunbergianaI)

Quality Level

100

Assay

≥98% (HPLC)

form

powder

technique(s)

HPLC: suitable

color

white to faint beige

mp

203 - 204  °C ((397 - 399 °F ))

solubility

10 mg, clear, colorless to faintly yellow

storage temp.

room temp

SMILES string

O=C1C2=CC(OC)=C(O[C@H]3[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O3)C=C2OC=C1C4=CC=C(O)C=C4

InChI

1S/C22H22O10/c1-29-15-6-12-14(30-9-13(18(12)25)10-2-4-11(24)5-3-10)7-16(15)31-22-21(28)20(27)19(26)17(8-23)32-22/h2-7,9,17,19-24,26-28H,8H2,1H3/t17-,19-,20+,21-,22-/m1/s1

InChI key

OZBAVEKZGSOMOJ-MIUGBVLSSA-N

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General description

Glycitin is an isoflavonoid recently found in flowers of Pueraria thunbergianaI. Glycitin can be modified into the metabolite glycitein which has anti-inflammatory properties.

Biochem/physiol Actions

Glycitin is a soy isoflavone in the glucoside form. A rat model study demonstrated glycitin to be effective in preventing bone loss and reversing the unfavorable changes of lipid metabolism in this model.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Isoflavone glycosides from the flowers of Pueraria thunbergiana.
Park HJ
Phytochemistry, 51, 147-151 (1999)
Kouya Yamaki et al.
Planta medica, 68(2), 97-100 (2002-02-23)
Previously, we reported that the isoflavones tectorigenin and tectoridin, a glycosylated tectorigenin, isolated from the rhizomes of Belamcanda chinensis have an activity to inhibit prostaglandin (PG) E2 production in 12-O-tetradecanoylphorbol 13-acetate (TPA)-stimulated rat peritoneal macrophages. The inhibitory effect of tectorigenin

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