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G1513

Glycerol formal

47-67% 5-hydroxy-1,3-dioxane basis (GC), 33-53% 4-hydroxymethyl-1,3-dioxolane basis (GC)

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About This Item

Empirical Formula (Hill Notation):
C4H8O3
CAS Number:
Molecular Weight:
104.10
UNSPSC Code:
50161901
NACRES:
NA.25
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
103206
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contains

~0.02% 2,6-di-tert-butyl-4-methylphenol as stabilizer

composition

5-hydroxy-1,3-dioxane, 47-67% GC , 4-hydroxymethyl-1,3-dioxolane, 33-53% GC

refractive index

n20/D 1.451 (lit.)

bp

192-193 °C (lit.)

density

1.203 g/mL at 25 °C (lit.)

SMILES string

OCC1COCO1.OC2COCOC2

InChI

1S/2C4H8O3/c5-4-1-6-3-7-2-4;5-1-4-2-6-3-7-4/h2*4-5H,1-3H2

InChI key

JIUMSISXCKWZTA-UHFFFAOYSA-N

General description

Glycerol formal (GlyF) includes isomers, namely, 4-hydroxymethyl-1,3-dioxolane and 5-hydroxy-1,3-dioxane. It is a glycerol synthon with a combination of two 5- and 6-membered ring isomers.

Application

Glycerol formal is used to to solubilize water-insoluble compounds for subsequent aqueous dilution. It has been used as a chemical and dye emulsifier and as a cosolvent for drug delivery
Glycerol formal is used to to solubilize water-insoluble compounds for subsequent aqueous dilution. It has been used as a chemical and dye emulsifier and as a cosolvent for drug delivery. Glycerol formal was used as a vehicle for antibiotic delivery in rats.


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Properties of fatty acid glycerol formal ester (FAGE) for use as a component in blends for diesel engines
Lapuerta M, et al.
Biomass and Bioenergy, 130-140 (2015)
Selective catalytic etherification of glycerol formal and solketal with dialkyl carbonates and K 2 CO 3
Selva M, et al.
Green Chemistry, 188-200 (2012)
Sarah Nickolls et al.
Advances in pharmacological sciences, 2011, 608912-608912 (2011-12-14)
GABA(A) receptors containing α2/3 subunits are current targets in the battle to develop new pain medications, as they are expressed in the spinal cord where increasing inhibitory drive should result in analgesia. However, this approach is prone to a range



Global Trade Item Number

SKUGTIN
G1513-250ML04061838179067
G1513-100ML04061833628218
G1513-1L04061838179050