G1514
D-(+)-Glucosamine hydrochloride
≥99%, BioReagent, suitable for cell culture
Synonym(s):
2-Amino-2-deoxy-D-glucose hydrochloride, Chitosamine hydrochloride
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About This Item
Empirical Formula (Hill Notation):
C6H13NO5 · HCl
CAS Number:
Molecular Weight:
215.63
PubChem Substance ID:
UNSPSC Code:
12352209
MDL number:
NACRES:
NA.75
EC Number:
200-638-1
Beilstein/REAXYS Number:
4157370
Quality Level
biological source
Aspergillus niger, maize fruit
product line
BioReagent
assay
≥99%
form
powder
technique(s)
cell culture | mammalian: suitable
mp
190-194 °C (dec.) (lit.)
solubility
water: 100 mg/mL, clear, colorless
SMILES string
Cl.N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O
InChI
1S/C6H13NO5.ClH/c7-3-5(10)4(9)2(1-8)12-6(3)11;/h2-6,8-11H,1,7H2;1H/t2-,3-,4-,5-,6?;/m1./s1
InChI key
QKPLRMLTKYXDST-NSEZLWDYSA-N
General description
Glucosamine, an amino sugar is generated form glucose and glutamine and is naturally produced in the body. Glucosamine, a endogenous amino monosaccharide is the major source of glucosamine-6-phosphate and n-acetylglucosamine.
Application
Glucosamine has been used as a standard to examine the concentration of glucosamine in the synovial fluid and its pharmacokinetics in serum.
Biochem/physiol Actions
Glucosamine is preferred as a nutritional supplement for individuals with osteoarthritis. It is used as a building block for the production of proteoglycans and glycosaminoglycans.
Glucosamine, an amino sugar, is the precursor of the hexosamine biosynthetic pathway leading to the formation of UDP-N-acetylglucosamine (UDP-GlcNAc), which is then used for making glycosaminoglycans, proteoglycans, and glycolipids. D-(+)-Glucosamine inhibits the coaggregation of Candida yeast species with the bacterial strain S. salivarius.
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Storage Class
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Glucosamine Chondroitin Sulfate
Saunders Handbook of Veterinary Drugs, 357-358 (2016)
Synovial fluid levels and serum pharmacokinetics in a large animal model following treatment with oral glucosamine at clinically relevant doses
Laverty S, et al.
Arthritis, 52(1), 181-191 (2005)
Nathaniel S Hwang et al.
Biomaterials, 27(36), 6015-6023 (2006-07-29)
Differentiation of embryonic stem (ES) cells generally occurs after formation of three-dimensional cell aggregates, known as embryoid bodies (EBs). We have previously reported that hydrogels provide EBs a supportive environment for in vitro chondrogenic differentiation and three dimensional tissue formation
Global Trade Item Number
| SKU | GTIN |
|---|---|
| G1514-500G | 04061833628232 |
| G1514-100G | 04061833628225 |