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Merck
CN

G1637

Sigma-Aldrich

Glucopsychosine

Synonym(s):

1-β-D-Glucosylsphingosine

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About This Item

CAS Number:
MDL number:
UNSPSC Code:
12352211
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storage temp.

−20°C

SMILES string

CCCCCCCCCCCCC\C=C\C(O)C(N)COC1OC(CO)C(O)C(O)C1O

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Preparation Note

Prepared from glucocerebrosides from human (Gaucher′s) spleen

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Chihiro Mogi et al.
Journal of pharmacological sciences, 99(2), 160-167 (2005-10-08)
Ovarian cancer G-protein-coupled receptor 1 (OGR1), previously proposed as a receptor for sphingosylphosphorylcholine (SPC), has recently been identified as a proton-sensing or extracellular pH-responsive G-protein-coupled receptor stimulating inositol phosphate production, reflecting the activation of phospholipase C. In the present study
Emyr Lloyd-Evans et al.
The Biochemical journal, 375(Pt 3), 561-565 (2003-08-15)
Recently, we demonstrated that the GSL (glycosphingolipid), GlcCer (glucosylceramide), modulates Ca2+ release from intracellular stores and from microsomes by sensitizing the RyaR (ryanodine receptor), a major Ca2+-release channel of the endoplasmic reticulum, whereas the lyso derivative of GlcCer, namely GlcSph
Genji Imokawa
Journal of dermatological science, 55(1), 1-9 (2009-05-16)
A deficiency of ordinary ceramides in the stratum corneum is an essential etiologic factor for the dry and barrier-disrupted skin of patients with atopic dermatitis (AD). We have proposed that the mechanism underlying that deficiency involves a novel sphingolipid metabolizing
Joseph K Park et al.
Pediatric research, 53(3), 387-395 (2003-02-22)
Gaucher disease, the inherited deficiency of lysosomal glucocerebrosidase, presents with a wide spectrum of manifestations. Although Gaucher disease has been divided into three clinical types, patients with atypical presentations continue to be recognized. A careful phenotypic and genotypic assessment of
U H Schueler et al.
Neurobiology of disease, 14(3), 595-601 (2003-12-18)
Patients with Gaucher disease have been classified as type 1 nonneuronopathic, type 2 acute neuronopathic, and type 3 chronic neuronopathic phenotypes. Increased quantities of glucocerebroside and glucosylsphingosine (glucopsychosine) are present in the brain of type 2 and type 3 Gaucher

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