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Merck
CN

G1763

β-Glutamic acid

≥98% (TLC), suitable for ligand binding assays

Synonym(s):

3-Aminopentanedioic acid

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About This Item

Empirical Formula (Hill Notation):
C5H9NO4
CAS Number:
Molecular Weight:
147.13
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.26
MDL number:
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Product Name

β-Glutamic acid,

assay

≥98% (TLC)

Quality Level

form

powder

technique(s)

ligand binding assay: suitable

color

white to off-white

SMILES string

NC(CC(O)=O)CC(O)=O

InChI

1S/C5H9NO4/c6-3(1-4(7)8)2-5(9)10/h3H,1-2,6H2,(H,7,8)(H,9,10)

InChI key

BBJIPMIXTXKYLZ-UHFFFAOYSA-N

Biochem/physiol Actions

β-Glutamic acid (β-Glu) is used as an osmolyte in many archaea. β-Glutamic acid may be used as a substrate to study the specificity and kinetics of archaeal and bacterial glutamine synthetase (GS) enzymes. β-Glutamic acid is used to study primitive mechanisms of polypeptide formation.


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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T Bayer et al.
Journal of peptide science : an official publication of the European Peptide Society, 7(5), 250-261 (2001-06-29)
A new synthesis of orthogonally protected diaminoglutaric acid containing peptides using the Ugi four component condensation is presented. To demonstrate that this method is useful to replace cystine by diaminoglutaric acid in biologically interesting peptides, we built up two cyclic
P Robinson et al.
Applied and environmental microbiology, 67(10), 4458-4463 (2001-09-26)
The conversion of beta-glutamate to beta-glutamine by archaeal and bacterial glutamine synthetase (GS) enzymes has been examined. The GS from Methanohalophilus portucalensis (which was partially purified) is capable of catalyzing the amidation of this substrate with a rate sevenfold less
H McLennan et al.
Neuropharmacology, 21(6), 549-554 (1982-06-01)
Separate receptors are recognized for the excitation of mammalian neurones by (a) L-glutamic and quisqualic acids and (b) N-methyl-D-aspartic (NMDA), and other amino acids which have conformationally restricted molecules. Several other compounds, both agonists and antagonists, have been examined, and



Global Trade Item Number

SKUGTIN
G1763-500MG04061833628355
G1763-100MG04061832416342
G1763-50MG04061832416366