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G1763

Sigma-Aldrich

β-Glutamic acid

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Synonym(s):
3-Aminopentanedioic acid
Empirical Formula (Hill Notation):
C5H9NO4
CAS Number:
1948-48-7
Molecular Weight:
147.13
MDL number:
MFCD00056698
PubChem Substance ID:
24895076
NACRES:
NA.26

Assay

≥98% (TLC)

Quality Level

100

form

powder

technique(s)

ligand binding assay: suitable

color

white to off-white

SMILES string

NC(CC(O)=O)CC(O)=O

InChI

1S/C5H9NO4/c6-3(1-4(7)8)2-5(9)10/h3H,1-2,6H2,(H,7,8)(H,9,10)

InChI key

BBJIPMIXTXKYLZ-UHFFFAOYSA-N

Related Categories

Biochem/physiol Actions

β-Glutamic acid (β-Glu) is used as an osmolyte in many archaea. β-Glutamic acid may be used as a substrate to study the specificity and kinetics of archaeal and bacterial glutamine synthetase (GS) enzymes. β-Glutamic acid is used to study primitive mechanisms of polypeptide formation.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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T Bayer et al.
Journal of peptide science : an official publication of the European Peptide Society, 7(5), 250-261 (2001-06-29)
A new synthesis of orthogonally protected diaminoglutaric acid containing peptides using the Ugi four component condensation is presented. To demonstrate that this method is useful to replace cystine by diaminoglutaric acid in biologically interesting peptides, we built up two cyclic
R Liu et al.
Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life, 28(3), 245-257 (1998-06-05)
We have studied the accumulation of long oligomers of beta-amino acids on the surface of minerals using the 'polymerization on the rocks' protocol. We find that long oligopeptides of beta-glutamic acid which cannot be formed in homogeneous aqueous solution are
D E Robertson et al.
Biochimica et biophysica acta, 992(3), 320-326 (1989-09-15)
13C- and 15N-NMR spectroscopy have been used to identify beta-aminoglutaric acid (beta-glutamic) as a major soluble component of the thermophilic, autotrophic marine methanogen Methanococcus thermolithotrophicus. This rare, non-protein amino acid has been recognized as a major dissolved free amino acid
Jean-François Lambert
Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life, 38(3), 211-242 (2008-03-18)
The present paper offers a review of recent (post-1980) work on amino acid adsorption and thermal reactivity on oxide and sulfide minerals. This review is performed in the general frame of evaluating Bernal's hypothesis of prebiotic polymerization in the adsorbed
D E Robertson et al.
Applied and environmental microbiology, 56(5), 1504-1508 (1990-05-01)
The unusual compound beta-aminoglutaric acid (beta-glutamate) has been identified by 13C nuclear magnetic resonance spectroscopy in soluble extracts of marine methanogenic bacteria. We examined several methanogen species representing nine genera and found that beta-glutamate occurred in methanococci and two methanogenium
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Chromatograms

application for HPLC

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